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婴幼儿接种百白破疫苗发生不良反应的原因分析
...sesinleadingtotheadversereactionsinbabiesandinfantsinjectedwithpertussis，diph-theriaandtetanusvaccines. CHENQian. （XinzhouCommunityCenterofFutianDistrictChronicDiseaseHos-pital，Shenzhen518000，Guangdong，P.R.China） 摘要:目的分析婴幼儿接种百白破疫苗发生不...
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成人用吸附精制白喉破伤风二联类毒素人体反应及血清学效果观察
...0145-03ObservationontheSideEffectandSerologicalEffectofAdult－typeTetanus-DiphtheriaCombinedVaccine(Td)LIUAi-hua，GUYin-hua，WANGChang-nian （BeijingEpidemicPreventionStation,Beijing100013,China.） Abstract:Sideeffectandserologicaleffectwereobservedin214primaryschoolchildrenwhowereino...
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EndotoxinInducesToll-LikeReceptor4ExpressioninVascularSmoothMuscleCellsviaNADPHOxidaseActivationandMitogen-ActivatedProteinKinaseSignaling
...ithpolyethylene-glycol-conjugatedsuperoxidedismutase,N-acetylcysteine(NAC),diphenyleneiodonium(DPI),orapocyninsignificantlydecreasedLPS-inducedTLR4expression.AnactinomycinDchaseexperimentshowedthatLPSincreasedthehalf-lifeofTLR4mRNA.InhibitionofNADPHoxidaseactivitybyDPI,apocynin,orNACsignificantlydec...
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OrganicCation/CarnitineTransporterOCTN2(Slc22a5)IsResponsibleforCarnitineTransportacrossApicalMembranesofSmallIntestinalEpithelialCellsinMo
...in,norepinephrine,histamine,-ketoglutarate,guanidine,N1-methylnicotinamide,diphenhydramine,procainamide,lidocaine,orpara-aminohippurate(Table1).ThisinhibitionprofileissimilartothatobservedforcarnitineuptakebyHEK293cellsstablytransfectedwithmouseOCTN2(Tamaietal.,2000;Ohashietal.,2001),exceptthat5mMno...
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ValidationoftheAnti-InflammatoryPropertiesofSmall-MoleculeIBKinase(IKK)-2InhibitorsbyComparisonwithAdenoviral-MediatedDeliveryofDominant-Nega
...ificanteffectoncellviabilityasdeterminedby3-[4,5-dimethylthiazol-2-yl]-2,5-diphe-nyltetrazoliumbromide(MTT)(Sigma)cellviabilityassay(Fig.1).Cellswerethenincubatedfor24handserum-starvedforanadditional24hbeforemicroscopicinspectiontoconfirmnormalmorphology.Thecellswerethentreatedwithcytokinesorprepare...
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2-AminoethoxydiphenylBorateDirectlyInhibitsChannelsComposedofConnexin26and/orConnexin32
【关键词】2-Aminoethoxydiphenyl2-Aminoethoxydiphenylborate(2-APB),acommonlyusedblockerofIP3-inducedcalciumionreleaseandofstore-operatedchannels,inhibitsgapjunctionconductancewhenappliedtoculturedcells.Thecharacterandpharmacologyofthisinhibitionwasexploredusing1)hemichannelscomposedofconnexin32(...