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抗胃食管反流外科治疗的远期疗效观察
...管反流外科治疗的远期疗效。研究者1988年11月至2004年1月手术治疗129例胃食管反流病(GERD)，分别采用Nissen手术(65例)、贲门斜行套叠术(39例)、Belsey4号手术(17例)、Toupet手术(3例)、Thal手术(1例)、Dor手术(4例)等6种方法治疗。116例得到...
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惠州地区地中海贫血调查
...词】地中海贫血；检出率；血红蛋白 SurveyofincidenceofthalassemiainHuizhouArea. WUYuan-zhong,YUXiao-yan,DINGFa-ying,etal. (HuizhouMunicipalCentralPeople’sHospital,Huizhou516001,Guangdong,P.R.China) Abstract:ObjectiveTosurveytheprevalenceofthalassemiainHu...
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Confocalmicroscopyofthecorneainnephropathiccystinosis
1AnteriorSegmentDivision,DepartmentofOphthalmology,KingKhaledEyeSpecialistHospital,Riyadh,KingdomofSaudiArabia2PediatricOphthalmologyandStrabismusDivision,DepartmentofOphthalmology,KingKhaledEyeSpecialistHospital,Riyadh,KingdomofSaudiArabiaKeywords:confocalmicroscopy;cornea;nephropathiccystinosisCys...
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糖尿病心血管疾病的非降脂治疗与临床评价
...ransplantn=64n=72n=80n=142n=149n=925n=43n=43PositiveETTPositiveAngiography(thal201)36%24%9%31%30%12.1%65%40%58%55%9%11%9%12.1%5.3%6.4%——35%43%IndicationsforCardiacTestinginDiabeticPatientsTypicaloratypicalcardiacsymptomsRestingECGsuggestiveofischemiaorinfarctionPeripheralorcarotidocclusivearteri...
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多囊卵巢综合征中西医结合诊疗浅议
...监测排卵，排卵率达89.7%，6个月的累计妊娠率为68.5%。3.4手术治疗3.4.1腹腔镜手术适用于严重PCOS对促排卵治疗无效者。在腹腔镜下对多囊卵巢用电凝或激光技术穿刺打孔，每侧卵巢打孔4个为宜，既能获得90%排卵率和70%妊娠率，又...
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多发性骨髓瘤治疗新突破
...、8、11,马法兰(Mel)0.15mg/kgd1~4,Dex12mg/m2d1~4、d17~20,沙利度胺(Thal)100mg/d,28天一周期]的VMDT方案治疗复发/难治性MM的Ⅱ期临床试验结果。该研究共有31例患者入组,其中20例为难治性复发患者,至报告时有25例患者可评价治疗反应,14例(56%)达...
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SuperoxideenhancesNa-K-2Clcotransporteractivityinthethickascendinglimb
...ichiganABSTRACTSuperoxide(O2)enhancesNareabsorptionbythethickascendinglimb(THAL).NaabsorptioninthissegmentinvolvestheNa-K-2Clcotransporter,Kchannel,andNa-K-ATPase.WehypothesizedthatO2stimulatesNaClabsorptionprimarilybyenhancingNa-K-2Clcotransport.First,wemeasuredsteady-stateintracellularNa(Nai)andch...
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广东顺德地区β-地中海贫血流行病学调查
...因突变；流行病学调查 Epidemiologicalinvestigationofβ-thalassemiainShundeAreaofGuangdong. XIEJian-min,LIANGYu-quan,WUSu-qin. ShundeDistrictFirstPeople’sHospitalofFoshanCity,Foshan528300,Guangdong,P.R.China Abstract：ObjectiveToinvestigatethecarryingrateandfre...
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LuminalflowinduceseNOSactivationandtranslocationintheratthickascendinglimb.II.RoleofPI3-kinaseandHsp9
...nthase(eNOS)regulatesNaClabsorptionbythethickascendinglimboftheloopofHenle(THAL).WefoundthataugmentingluminalflowinduceseNOSactivationandtranslocationtotheapicalmembraneofTHALs(OrtizPA,HongNJ,andGarvinJL.AmJPhysiolRenalPhysiol287:F274-F280,2004).Inothercells,eNOSactivationbyshearstressismediatedbyph...
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食管裂孔疝（外科）
...，而非食管运动障碍所致。长时pH监测法：以前作过食管手术的病人，合并其他疾病者，怀疑有返流引起吸入性肺炎或患“心绞痛”的病人，为其使用24hpH连续监测可提供宝贵的诊断资料。作系列标准的食管功能试验测定后，pH电...
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环境雌激素的研究进展
...tylphenol）和壬基酚（4-Nonylphenol）等;（5）酞酸酯类（PAEsphthalates）:其中DEP，DMP和DOP已被我国确定为环境优先控制污染物［3］。（6）金属化合类:目前以三丁基锡研究较多。 （7）其它环境激素类。 2EEs对人体健康的危害和...
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EvaluationofRibotypingasaToolforMolecularTypingofYersiniapseudotuberculosisStrainsofWorldwideOrigin
...ndY.enterocoliticaInfectionsinSheepinAustralia.J.Clin.Microbiol.30:712-715.Thal,E.1973.ObservationsonimmunityinYersiniapseudotuberculosis.Contrib.Microbiol.Immunol.2:190-195.Toyokawa,Y.,Y.Ohtomo,T.Akiyama,K.Masuda,M.Kasai,S.Kaneko,andT.Maruyama.1993.LargescaleoutbreakofYersiniapseudotuberculosissero...
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Bonecalciumturnoverduringpregnancyandlactationinwomenwithlowcalciumdietsisassociatedwithcalciumintakeandcirculatinginsulin-likegrowthfac
...analyses.JCKwasresponsiblefortheconceptionandfundingofthestudyandassistedwithallaspectsofthestudyimplementationandanalysisandwiththemanuscriptpreparation.Noneofthestudyauthorshadanypersonalorfinancialaffiliationswiththesupporterofthisresearch.REFERENCESReceivedforpublicationJuly25,2005.Acceptedforpu...
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Endothelinstimulatesendothelialnitricoxidesynthaseexpressioninthethickascendinglimb
...Endothelin-1(ET-1)acutelyinhibitsNaClreabsorptionbythethickascendinglimb(THAL)byactivatingtheETBreceptor,stimulatingendothelialnitricoxidesynthase(eNOS),andreleasingnitricoxide(NO).Innonrenaltissue,chronicexposuretoET-1stimulateseNOSexpressionviatheETBreceptorandactivationofphosphatidylinositol3-kin...
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ClonalSpreadofaVancomycin-ResistantEnterococcusfaeciumStrainamongBloodstream-InfectingIsolatesinItaly
...trophoresis:criteriaforbacterialstraintyping.J.Clin.Microbiol.33:2233-2239.Thal,L.,S.Donabedian,B.Robinson-Dunn,J.Chow,L.Dembry,D.Clewell,D.Alshab,andM.Zervos.1998.Molecularanalysisofglycopeptide-resistantEnterococcusfaeciumisolatescollectedfromMichiganhospitalsovera6-yearperiod.J.Clin.Microbiol.36:...
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Ahigh-saltdietstimulatesthickascendinglimbeNOSexpressionbyraisingmedullaryosmolalityandincreasingreleaseofendothelin-1
...TAhigh-saltdietincreasesrenalendothelin(ET)productionandthickascendinglimb(THAL)endothelialnitricoxidesynthase(eNOS)expression.ETstimulatesTHALeNOSexpressionviaETBreceptors.Thetonicityoftherenalmedullaishighlyvariable,andhyperosmolalitystimulatesET-1synthesisbyendothelialcells.Wehypothesizedthatahig...
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CharacterizationofVancomycin-ResistantEnterococcusfaeciumIsolatesfromBroilerPoultryandPigFarmsinEnglandandWales
...EFisolateswereselectedbytheircolonymorphologyandcolor(purple-pinkcolonieswithalighterhalo),subcultured,andstoredat–70°C.TheidentityofthepresumptiveE.faeciumisolateswasconfirmedbyreal-timePCR.AmplificationwasperformedinaLightCyclerinstrument(RocheDiagnosticsUKLtd.,Lewes,UnitedKingdom)inglasscapill...
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肾综合征出血热流行病学研究进展
...和捷克的Tula病毒宿主为欧洲的普通田鼠。带Thottapalayan和THAL的宿主动物仅在南亚和东南亚分布［27］。日本HV的宿主为棕背平鼠、褐家鼠、黑家鼠和大林姬鼠［17］。欧洲DOB病毒宿主为黑线姬属和黄颈姬鼠［26］。我国HFRS疫源地监...
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Aminoglycoside-InducedDegenerationofAdultSpiralGanglionNeuronsInvolvesDifferentialModulationofTyrosineKinaseBandpNeurotrophinReceptorSignali
...ionindegeneratingSGNs,concomitantwithatemporaldeclineofSGNdensityintheRosenthal??scanalwherethesemolecularchangesoccur.Coincidentally,theproportionofdegeneratingneuronsexpressingphosphorylatedc-Jun,atargetofp75NTR-mediatedpathway,27,28isincreased,whereasthereisaconversedeclineintheproportionofneuron...
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ThalidomideasaPotentInhibitorofNeointimalHyperplasiaAfterBalloonInjuryinRatCarotidArtery
...isoneofthemainpathogenesesofneointimalhyperplasiaaftercoronaryintervention.Thalidomide,becauseofitspotentantiinflammatoryandimmunomodulatoryproperties,isbeingre-evaluatedinseveralclinicalfields.Therefore,weexaminedwhetherthalidomidetherapyaffectsneointimalformation.MethodsandResults—InmaleSprague-...
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Regulationofthickascendinglimbtransport:roleofnitricoxide
...ecteffectsofnitricoxide(NO)onindividualtransportersofthethickascendinglimb(THAL)cell.NOdirectlyinhibitsNa+-K+-2Cl-cotransportandNa/Hexchangers(NHE1/3).NOinhibitstheNa+-K+-ATPasepumpbyreactingwithO2-andformingOONO-.TheeffectofNOoninwardlyrectified(ROMK)channelsremainscontroversial.(-),Inhibition;(?),...
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RenewalofMuralThrombusReleasesPlasmaMarkersandIsInvolvedinAorticAbdominalAneurysmEvolution
...emedia,andahigherlevelofimmuno-inflammationintheadventitia.6Thiscontrastswithalowerlevelofproteaseactivitieswithinthethrombus-exposedarterialwallascomparedwiththewallnotexposedtothrombusactivity.7Themuralthrombusisenrichedwithplasminogen-plasmin,3andfibrinolysispredominatesintheabluminalpartofthethr...
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MiceDeficientfortheTypeIITransmembraneSerineProteaseTMPRSS/hepsinExhibitProfoundHearingLoss
...eobtainedandstainedwithhematoxylinandeosin.Thecross-sectionalareaoftheRosenthal??scanal,osseousspirallamina,andtectorialmembranefromthemiddleturnweredeterminedusingamorphometricprogram(AxioVisionLE,Hallbergmoos,Germany).Thesameprogramwasalsousedtomeasurethelongestverticaldistancebetweenthedorsalandv...
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BK-1subunit:immunolocalizationinthemammalianconnectingtubuleanditsroleinthekaliureticresponsetovolumeexpansion
...l.(41)demonstratedflow-activatedeNOSandNOproductioninthethickascendinglimb(THAL).WeandothersshowedthatBKareactivatedbytheNO-cGMP-proteinkinaseGpathway(1,51,52)andthatthisactivationrequiresthepresenceofaBK-1orBK-2subunit(22,61).Weobservednearlyadoublingoftheopenprobability(PO)oncGMPadditioninanexpres...
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ImpairmentofFunctionalCapillaryDensitybutNotOxygenDeliveryintheHamsterWindowChamberduringSevereExperimentalMalaria
...ribundcomparedwithuninfectedcontrols,butthislevelwasmarkedlyhigherthanthelethalthreshold.Nonecroticcellslabeledwithpropidiumiodideweredetectedinmoribundanimalsonday10afterinfection.Wethereforeconcludethatlossoffunctionalcapillariesratherthantissuehypoxiaisamajorlethaleventinseveremalaria.-----------...
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PharmacologicalTargetingofAdipocytes/FatMetabolismforTreatmentofObesityandDiabetes
...persons.Additionalconsiderationstothetherapeuticuseofleptinaretherathershorthalf-lifeofthepeptideinhumans(25min)(Kleinetal.,1996),thehighcostofproduction,andtheneedforinjections,allfactsthatmaketheuseofleptinintheclinicproblematicforroutineusage.Theseconsiderationsalsoapplytoadiponectinandretinolbin...
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InhibitionofNa-K-ATPaseinthickascendinglimbsbyNOdependsonO2-andisdiminishedbyahigh-saltdiet
...nhancesnitricoxide(NO)-inducedinhibitionoftransportinthethickascendinglimb(THAL).LongexposurestoNOinhibitNa-K-ATPaseinculturedcells.WehypothesizedthatNOinhibitsTHALNa-K-ATPaseafterlongexposuresandahigh-saltdietwouldaugmentthiseffect.Ratsdrankeithertapwateror1%NaClfor7-10days.Na-K-ATPaseactivitywasas...
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手术室医院信息系统的建立与应用体会
【摘要】目的建立手术室医院信息系统(HIS)，以保证围手术期患者管理和手术部的安全运转，达到信息及时准确传递及手术相关的统计工作的目的。方法在医院信息系统运行中逐步优化和完善手术申请、手术安排、手术登记、手...
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优化手术室业务流程提升手术台利用率
【摘要】 目的找出目前手术室工作的流程中存在的问题，根据问题优化手术室工作流程，提高工作效率。方法运用业务流程再造的技术和方法，对原有的第一台手术不能按时开始、连台手术间隔时间太长等不合理的工作流程...
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接台手术的护理问题及对策分析
【摘要】探讨手术室接台手术中存在的护理问题，加强接台手术中的护理。根据所存在的护理问题，进行相应的对策分析，确保手术患者的安全。【关键词】接台手术;护理问题;对策分析随着手术量的不断增加，手术室手术的接...