心气虚，则脉细；肺气虚，则皮寒；肝气虚，则气少；肾气虚，则泄利前后；脾气虚，则饮食不入。
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Ikarostranscriptionfactors:flyingbetweenstressandinflammation
...rhombotin-2;SCL,stemcellleukemia;SF-1,steroidogenicfactor1;TCF,Tcellfactor;Tpit,pituitarycell–restrictedTboxfactor.FiguremodifiedwithpermissionfromCell(6)andAnnualReviewofNeuroscience(11).IkarosisoformsshareacommonC-terminalpart,containingabipartitetransactivationdomainand2zincfingermotifs,whichme...
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Ikarosintegratesendocrineandimmunesystemdevelopment
...mentintoadulthood.AtE15.5,developingcorticomelanotrophcellswereidentifiedbyTpitexpressionattheperipheryoftheglandaspreviouslydescribed(11).AtE17.5,POMCexpressionwasreducedinIkaros-heterozygousmiceandwasalmostundetectableinIkaros-null(–/–)micedespitethepresenceofnormalTpitexpression(Figure4A).Fig...