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地中海贫血的诊治进展
...遍应用MCV和红细胞渗透脆性试验(Redcellosmoticfragilitytest,ROFT)低于正常值来初筛地贫携带者。地贫携带者的筛查方法有很多,但各有利弊。目前临床上应用最为广泛的还是红细胞指数分析法。地贫基因携带者通常表现为小细胞...
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Samestagereconstructionofthetissuedefectswithislandmyocutaneousflapinheadandnecksurgery
...tructingrangeinenlarginglocalresectionandtheareaofdispensingwithalargenumberoftissueassuchrepairingregionofcheek,posteriormolarandzygomapicfaceaswehaddoneitinourgroup.Thepedicleofmyocutaneousflapwaspassedintoreceivingareawiththeshortestapproachandtwotunnels;subskintunnelsofinteriorlateralof...
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AntiviralTcellresponses:phalanxormultiprongedattack
...arimmunityagainstcytomegalovirusinrecipientsofallogeneicbonemarrowbytransferofT-cellclonesfromthedonor.N.Engl.J.Med.333:1038–1044.Basta,S.,andJ.R.Bennink.2003.Asurvivalgameofhideandseek:cytomegalovirusesandMHCclassIantigenpresentationpathways.ViralImmunol.16:231–242.Tabi,Z.,M.Moutaftsi,andL.K.Bo...
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ImportanceofEarlyIschemicComputedTomographyChangesUsingASPECTSinNINDSrtPAStrokeStudy
...mptomonset,theNINDSinvestigatorsshoweda31%EICprevalenceandEICwasnotamodifierofthetreatmenteffect.ThedetectionofEICwaslowwhencomparedwithotherstudies,althoughthismaybetheresultofearlierCTscanninginthe0-to3-hourwindowtrialcomparedwiththeother0-to6-hourtrials.7,8Furthermore,theconceptthattheriskofICHaf...
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Adoptivetransferofcytomegalovirus-specificCTLtostemcelltransplantpatientsafterselectionbyHLA–peptidetetramers
...ientsbeforeinfusion.ThelackofsignificantGvHDreflectstransferofaverylownumberofTcellswithantigenicspecificityotherthanthatforCMV.Atotaldoseof1.2x104to2x106CMV-specificTcellswasadministered;thisismuchsmallerthaninotheradoptivetransferprotocolswhereupto109Tcellsaregiven.However,thisnumbermaybesufficien...
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VascularEndothelialGrowthFactor–ExpressingMesenchymalStemCellTransplantationfortheTreatmentofAcuteMyocardialInfarction
...issuggestedtoplayimportantrolesinembryonicventriculardevelopment,24thenumberofTnT-positivecellsisnotsomuchandVEGFdidnotchangethenumberofthecells.Theseeffectsofcellulartransplantationmaycontributetothepreventionofinfarctexpansionandprogressiveventricularremodeling.WehavealsoshownthatexpressionofVEGFw...