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Plummer-Vinson综合征
【概述】Plummer-Vinson综合征又称Paterson-Kelly综合征或缺铁性吞咽困难，以缺铁性贫血、吞咽困难和舌炎为主要表现，好发于30～50岁的白种妇女性，男性少见，中国人罕见。【诊断】1.有缺铁性贫血、吞咽困难、舌炎的临床表现。2....
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老年缺铁性贫血
...成贫血。临床表现除一般缺铁贫血的表现外，吞咽疼痛（Plummer-Vinson综合症），舌粘膜萎缩及口角皱裂发生率较高。诊断病史：有导致铁摄入不足及吸收不良，排出增多等病因，实验室检查；小细胞低色素性贫血：MCV80μm3；血清...
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35 营养与口腔疾病--35.1营养与牙颌系统的发育
...，可有舌炎与溃疡，咽下困难，是普文（Plummer-Vinson）氏综合征之一。 （4）慢性胃炎慢性胃炎当营养缺乏时常见口腔症状有舌炎（舌发红光亮，中央后部出现血斑，称结节样舌炎）、阿弗它口炎、唇炎、龈炎。 （5）肝...
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31.1膳食中营养素与癌瘤发生的关系
...能与铁缺乏有关。瑞典北部曾流行Plummer-Vinson(Paterson-Kelly)综合征，该病是以缺铁性低血色素性贫血伴有咽下困难为特点。从瑞典北部地区1959～1974年女性口腔及咽下部（食道上部）肿瘤发病率来看，75%的咽下部癌瘤及25%口腔癌瘤...
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第六节 老年贫血
...临床表现的特点：除一般缺铁贫血的表现外，吞咽疼痛（Plummer-Vinson综合症），舌粘膜萎缩及口角皱裂发生率较高。 3．诊断：病史：有导致铁摄入不足及吸收不良，排出增多等病因，实验室检查；小细胞低色素性贫血：MCV<80...
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放射性131I治疗甲状腺机能亢进症
...例，女32例。其中Graves病31例，多结节毒性甲状腺肿13例，Plummer病9例。以下患者除外:（1）妊娠及哺乳期妇女;（2）未生育妇女;（3）近期心肌梗死［2］。 1.2治疗前准备（1）禁食含高碘食物及药物2周以上，做摄131I率试验，并测...
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NEJM：埃博拉疫苗测试结果理想未见严重副作用
...tz,ZonghuiHu,GyanJoshi,AuréliePloquin,SandraSitar,IngeliseJ.Gordon,SarahA.Plummer,LaSonjiA.Holman,CynthiaS.Hendel,GalinaYamshchikov,FrancoisRoman,AlfredoNicosia,StefanoColloca,RiccardoCortese,RobertT.Bailer,RichardM.Schwartz,MarioRoederer,JohnR.Mascola,RichardA.Koup,NancyJ.Sullivan,BarneyS.Graham.C...
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科学家宣布埃博拉疫苗初步通过人体测试
...tz,ZonghuiHu,GyanJoshi,AuréliePloquin,SandraSitar,IngeliseJ.Gordon,SarahA.Plummer,LaSonjiA.Holman,CynthiaS.Hendel,GalinaYamshchikov,FrancoisRoman,AlfredoNicosia,StefanoColloca,RiccardoCortese,RobertT.Bailer,RichardM.Schwartz,MarioRoederer,JohnR.Mascola,RichardA.Koup,NancyJ.Sullivan,BarneyS.Graham.C...
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甲状腺功能亢进症的治疗
...，又称Graves病，最为常见；②结节性毒性甲状腺肿，又称Plummer病；③毒性甲状腺瘤或高功能腺瘤。此外甲状腺瘤、亚急性或慢性甲状腺炎及某些类型的垂体肿瘤和卵巢肿瘤亦可伴发甲亢。我们主要对甲亢病的治疗进行探讨。对...
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加拿大“小诺贝尔奖”公布
...大盖尔德纳全球健康奖。加拿大公共健康局特别顾问FrankPlummer获得了加拿大盖尔德纳怀特曼奖。该奖项有“小诺贝尔奖”之称，至今300多名获奖者中已经有80名后来获得了诺贝尔生理学或医学奖。加拿大盖尔德纳奖于1959年由加拿...
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第二节 贫血
...于温反应自身抗体所致获得性溶血性贫血（2）冷凝集素综合征（3）阵发性冷性血红蛋白尿（4）药物诱发的免疫性溶血性贫血（5）新生儿同种[异体]免疫性溶血性疾病5、单核巨噬细胞机能亢进脾机能亢进6、失血急性失血性贫血...
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porVariable-RegionTypingbyDNAProbeHybridizationIsBroadlyApplicabletoEpidemiologicStudiesofNeisseriagonorrhoeae
...outermembranesasmodelsystems.JohnWileySons,Inc.,NewYork,N.Y.Brunham,R.C.,F.Plummer,L.Slaney,F.Rand,andW.DeWitt.1985.CorrelationofauxotypeandproteinItypewithexpressionofdiseaseduetoNeisseriagonorrhoeae.J.Infect.Dis.152:339-343.Carbonetti,N.H.,V.I.Simnad,H.S.Seifert,M.So,andP.F.Sparling.1988.Geneticso...
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甲状腺高功能腺瘤患者脑血流动力学变化
...比较（略） 3讨论 高功能腺瘤临床较少见，又称Plummer病。甲状腺腺体内出现单个的自主性高功能结节，不受促甲状腺激素（TSH）的调节。合并出现甲亢症状，病因尚未明确，可能是结节本身自主的分泌紊乱所致。患者心...
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超声多普勒检查技术在甲状腺功能亢进症患者中的临床应用价值
...因导致甲状腺功能增强，分泌过多甲状腺激素所致的临床综合征。临床上以高代谢、精神神经兴奋、甲状腺肿大为特征。引起甲状腺功能亢进的原因诸多，主要有毒性弥漫性甲状腺肿（Graves病）、多结节性甲状腺肿伴甲亢（Plumme...
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甲状腺功能亢进症的治疗
...又称Graves病，最为常见;（2）结节性毒性甲状腺肿，又称Plummer病;（3）毒性甲状腺瘤或高功能腺瘤。此外甲状腺瘤、亚急性或慢性甲状腺炎及某些类型的垂体肿瘤和卵巢肿瘤亦可伴发甲亢。本文主要对甲亢病的治疗进行探讨。对...
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Bacterialtoxinsandtheimmunesystem:showmetheinvivotargets
...onoftheehrlichiaAnaplasmamarginale.MicrobesInfect.2:167–176.Brunham,R.,F.Plummer,andR.Stephens.1993.Bacterialantigenicvariation,hostimmuneresponse,andpathogen-hostcoevolution.Infect.Immun.61:2273–2276.Zambrano-Villa,S.,D.Rosales-Borjas,J.C.Carrero,andL.Ortiz-Ortiz.2002.Howprotozoanparasitesevade...
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Ironstatusandexercise
...tis,angularstomatitis,koilonychia(spoonnails),bluesclera,esophagealwebbing(Plummer-Vinsonsyndrome),andanemia.Behavioraldisturbancessuchaspica[abnormalconsumptionofdirt(geophagia)andice(pagophagia)]areoftenpresentinpersonswithirondeficiency,althoughabiologicexplanationislacking.Itisalsoimportanttodel...
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膝部骨折脱位合并腘动脉损伤21例
...折脱位造成的钝性腘动脉损伤患者中常不出现或不明显。Plummer等［3］认为仔细的体格检查能使75％需要手术修复的血管损伤患者明确诊断。动脉造影是血管损伤诊断的金标准，但因造影检查可以延迟重建血液循环的时间1～2h，...
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Renalaseisanovel,solublemonoamineoxidasethatregulatescardiacfunctionandbloodpressure
...pressionusinggenomesequencedata.J.Biol.Chem.277::3593-3598.Binda,C.,Newton-Vinson,P.,Hubalek,F.,Edmondson,D.E.,andMattevi,A.2002..StructureofhumanmonoamineoxidaseB,adrugtargetforthetreatmentofneurologicaldisorders.Nat.Struct.Biol.9::22-26.Jalkanen,S.,andSalmi,M.2001..Cellsurfacemonoamineoxidases:enz...
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NovelAssayUsingTotalHepatitisCVirus(HCV)CoreAntigenquantificationforDiagnosisofHCVInfectioninDialysisPatients
...her.18:1071-1081.Fabrizi,F.,P.Martin,V.Dixit,M.Brezina,M.J.Cole,S.Gerosa,S.Vinson,M.Mousa,andG.Gitnick.1998.QuantitativeassessmentofHCVloadinchronichemodialysispatients:across-sectionalsurvey.Nephron80:428-434.Gretch,D.R.,L.Corey,C.delaRosa,andR.L.Carithers.1996.AssessmentofhepatitisCviremiausingmol...
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联合作用特征的评价
...平线Q（x）＝1为相加作用。 Finney在1962年最先提出，Plummer和Short后又加以改进的多药物联用的计算机分析模型［36］，区分相加作用中的协同还是拮抗，适用于质反应或量反应(经概率单位或对数转换)资料，不须预先掌握精确...
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ExpressionandImmunologicalCharacterizationoftheCarboxy-TerminalRegionoftheP1AdhesinProteinofMycoplasmapneumoniae
...VarshneyandPramodKumarfortheirassistance.REFERENCESBaseman,J.B.,J.Morrison-Plummer,D.Drouillard,B.Puleoscheppke,V.V.Tryon,andS.C.Holt.1987.Identificationof30-kilodaltonproteinofMycoplasmapneumoniaeassociatedwithhemadsorption.IsraelJ.Med.Sci.23:474-479.Chaudhry,R.,A.B.Dey,etal.2002.Community-acquired...
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PotentialLimitationsofthe16S-23SrRNAIntergenicRegionforMolecularDetectionofBartonellaSpecies
...fever(B.quintana)(9,40),endocarditis(B.elizabethae,B.henselae,B.quintana,B.vinsoniisubsp.arupensis,B.vinsoniisubsp.berkhoffii,andB.washoensis)(13,15,16,20),bacillaryangiomatosisinimmunocompromisedpatients(B.quintanaandB.henselae)(12,28,51),andcatscratchdisease(B.henselaeandB.clarridgeiae)(3,30,42).I...
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GeneticTypingofthePorinProteinofNeisseriagonorrhoeaefromClinicalNonculturedSamplesforStrainCharacterizationandIdentificationofMixedGonococ
....Fudyk,T.C.,I.W.Maclean,J.N.Simonsen,E.N.Njagi,J.Kimani,R.C.Brunham,andF.A.Plummer.1999.GeneticdiversityandmosaicismattheporlocusofNeisseriagonorrhoeae.J.Bacteriol.181:5591-5599.Giles,J.A.,J.Falconio,J.D.Yuenger,J.M.Zenilman,M.Dan,andM.C.Bash.2004.Quinoloneresistance-determiningregionmutationsandpor...
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DevelopmentandEvaluationofaMultitargetReal-TimeTaqmanReverseTranscription-PCRAssayforDetectionoftheSevereAcuteRespiratorySyndrome-Associated
...rescu,A.G.Robertson,J.E.Schein,A.Siddiqui,D.E.Smailus,J.M.Stott,G.S.Yang,F.Plummer,A.Andonov,H.Artsob,N.Bastien,K.Bernard,T.F.Booth,D.Bowness,M.Czub,M.Drebot,L.Fernando,R.Flick,M.Garbutt,M.Gray,A.Grolla,S.Jones,H.Feldmann,A.Meyers,A.Kabani,Y.Li,S.Normand,U.Stroher,G.A.Tipples,S.Tyler,R.Vogrig,D.Ward...
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IdentificationofImmunodominantEpitopesontheMembraneProteinoftheSevereAcuteRespiratorySyndrome-AssociatedCoronavirus
...rescu,A.G.Robertson,J.E.Schein,A.Siddiqui,D.E.Smailus,J.M.Stott,G.S.Yang,F.Plummer,A.Andonov,H.Artsob,N.Bastien,K.Bernard,T.F.Booth,D.Bowness,M.Czub,M.Drebot,L.Fernando,R.Flick,M.Garbutt,M.Gray,A.Grolla,S.Jones,H.Feldmann,A.Meyers,A.Kabani,Y.Li,S.Normand,U.Stroher,G.A.Tipples,S.Tyler,R.Vogrig,D.Ward...
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EnhancedCCAAT/Enhancer-BindingProtein-Liver-EnrichedInhibitoryProteinProductionbyOltipraz,WhichAccompaniesCUGRepeat-BindingProtein-1(CUGBP1)RNA
...minant-negativeexpressionplasmidofC/EBP(AC/EBP)andpCMV500weregiftsfromDr.C.Vinson(NationalInstitutesofHealth,Bethesda,MD).pCDNA-C/EBP,whichencodesratC/EBP,wasconstructedasdescribedpreviously(ChoandKim,2003).pCDNA-C/EBP-LAP2-M3L,inwhichthethirdstartcodonofC/EBPwasmutatedtothecodonforleucine,wasprepar...
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Sodiumchannelmutationsinepilepsyandotherneurologicaldisorders
...isulfide-linkedauxiliarysubunitwithsimilarityto?2.J.Neurosci.23::7577-7585.Plummer,N.W.,andMeisler,M.H.1999..Evolutionanddiversityofmammaliansodiumchannelgenes.Genomics.57::323-331.Goldin,A.L.2001..Resurgenceofsodiumchannelresearch.Annu.Rev.Physiol.63::871-894.Scheffer,I.,andBerkovic,S.F.1997..Gener...
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ComparisonbetweentheHybridCaptureIITestandaPCR-BasedHumanPapillomavirusDetectionMethodforDiagnosisandPosttreatmentFollow-UpofCervicalIntr
...igh-gradecervicallesions.Br.J.Cancer90:1803-1808.Clifford,G.M.,J.S.Smith,M.Plummer,N.Munoz,andS.Franceschi.2003.Humanpapillomavirustypesininvasivecervicalcancerworldwide:ameta-analysis.Br.J.Cancer88:63-73.Cuzick,J.,E.Beverley,L.Ho,G.Terry,H.Sapper,I.Mielzynska,A.Lorincz,W.K.Chan,T.Krausz,andP.Soutte...
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TransmissionandaccumulationofCTLescapevariantsdrivenegativeassociationsbetweenHIVpolymorphismsandHLA
...llespie,G.M.,R.Kaul,T.Dong,H.B.Yang,T.Rostron,J.J.Bwayo,P.Kiama,T.Peto,F.A.Plummer,A.J.McMichael,andS.L.Rowland-Jones.2002.Cross-reactivecytotoxicTlymphocytesagainstaHIV-1p24epitopeinslowprogressorswithB*57.AIDS.16:961–972.Draenert,R.,S.LeGall,K.J.Pfafferott,A.J.Leslie,P.Chetty,C.Brander,E.C.Holme...