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不同术式一期修复男童尿道下裂
...，带蒂包皮皮瓣相嵌(Onlay)9例，尿道口近端带蒂皮瓣翻卷(Mathieu)7例，尿道口前移(MAGPI)5例。结果术后发生尿瘘19例，尿道外口狭窄1例，总成功率90.2%。总并发症发生率9.8%。其中Duckett术式并发症7.8%(10/127)，阴茎原位皮管12.5%(2/16)，M...
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先天性尿道下裂治疗现状
...甚至退回至冠状沟。2尿道口基底血管皮瓣尿道成形术（Mathieu术） 1932年Mathieu报道后，已被广泛采用。适用于冠状沟及尿道口位于阴茎体前1/3的无阴茎下弯的前尿道下裂，手术成功率高，术后阴茎外观好，其方法为：在尿道...
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全球糖尿病专家联盟呼吁坚决加强糖尿病治疗以帮助预防灾难性的难以承受的全球负担
...者的治疗变得更加成功比利时卢维思大学(UniversityofLeuven)Mathieu教授评论道“胰岛素是已知的最为有效的降糖疗法，但是这种疗法目前却未得到有效使用。让人感到悲哀的是，II型糖尿病患者已经对胰岛素产生了恐惧，而不是把...
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肝脓肿MR诊断（附12例报告）
...组织炎性增生反应形成肉芽肿并纤维包膜。（2）环征，Mathieu等其看作肝脓肿的特征性表现［3］。环征可以是单环、双环甚至三环。三个环相当于脓肿壁的三种病理结构:即水肿，纤维肉芽组织或炎性坏死组织［1］。Mathieu等［3...
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HypercapnicAcidosisImpairsPlasmaMembraneWoundResealinginVentilator-injuredLungs
...itCareMed1998;157:294eC323.FuZ,CostelloML,TsukimotoK,PredilettoR,ElliottAR,Mathieu-CostelloO,WestJB.Highlungvolumeincreasesstressfailureinpulmonarycapllaries.JApplPhysiol1992;73:123eC133.CostelloML,Mathieu-CostelloO,WestJB.Stressfailureofalveolarepithelialcellsstudiedbyscanningelectronmicroscopy.AmR...
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CellularStressFailureinVentilator-injuredLungs
...RespirDis1985;132:880eC884.FuZ,CostelloML,TsukimotoK,PredilettoR,ElliottAR,Mathieu-CostelloO,WestJB.Highlungvolumesincreasesstressfailureinpulmonarycapllaries.JApplPhysiol1992;73:123eC133.CostelloML,Mathieu-CostelloO,WestJB.Stressfailureofalveolarepithelialcellsstudiedbyscanningelectronmicroscopy.Am...
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肝脓肿的CT诊断
...成。本组病例环靶征、蜂窝征和簇状征多以静脉期明显。Mathieu等和Jeffrey等认为环靶征、簇状征是肝脓肿的特征。本组静脉期增强1例病灶周围有斑片状明显不均强化，且供血肝动脉持续显影，提示病灶周围门静脉血流减少，另一...
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ShortcutMethodforExtractionofStaphylococcusaureusDNAfromBloodCulturesandConventionalCulturesforUseinReal-TimePCRAssays
...lturebottles.Diagn.Microbiol.Infect.Dis.41:165-168.Louie,L.,J.Goodfellow,P.Mathieu,A.Glatt,M.Louie,andA.E.Simor.2002.Rapiddetectionofmethicillin-resistantstaphylococcifrombloodculturebottlesbyusingamultiplexPCRassay.J.Clin.Microbiol.40:2786-2790.Maes,N.,J.Magdalena,S.Rottiers,Y.DeGheldre,andM.J.Stru...
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DetectionofMethicillin-ResistantStaphylococcusaureus(MRSA)inBloodwiththeEVIGENEMRSADetectionKit
...lturebottles.Diagn.Microbiol.Infect.Dis.41:165-168.Louie,L.,J.Goodfellow,P.Mathieu,A.Glatt,M.Louie,andA.E.Simor.2002.Rapiddetectionofmethicillin-resistantstaphylococcifrombloodculturebottlesbyusingamultiplexPCRassay.J.Clin.Microbiol.40:2786-2790.Maes,N.,J.Magdalena,S.Rottiers,Y.DeGheldre,andM.J.Stru...
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EvaluationoftheLightCyclerStaphylococcusMGRADEKitsonPositiveBloodCulturesThatContainedGram-PositiveCocciinClusters
...lturebottles.Diagn.Microbiol.Infect.Dis.41:165-168.Louie,L.,J.Goodfellow,P.Mathieu,A.Glatt,M.Louie,andA.E.Simor.2002.Rapiddetectionofmethicillin-resistantstaphylococcifrombloodculturebottlesbyusingamultiplexPCRassay.J.Clin.Microbiol.40:2786-2790.Oliveira,K.,G.W.Procop,D.Wilson,J.Coull,andH.Stender.2...
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StaytunedtoPXR:anorphanactorthatmaynotbeD-structiveonlytobone
...enin-angiotensinsystem.J.Clin.Invest.110::229-238.doi:10.1172/JCI200215219.Mathieu,C.,Waer,M.,Laureys,J.,Rutgeerts,O.,andBouillon,R.1994..PreventionofautoimmunediabetesinNODmiceby1,25dihydroxyvitaminD3.Diabetologia.37::552-558.McGrath,J.2001..Does‘imprinting’withlowprenatalvitaminDcontributetoth...
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SensitivityandSpecificityofaRapidrRNAGeneProbeAssayforSimultaneousIdentificationofStaphylococcusaureusandDetectionofmecA
...egativestaphylococci.J.Clin.Microbiol.39:4149-4151.Louie,L.,J.Goodfellow,P.Mathieu,A.Glatt,M.Louie,andA.E.Simor.2002.RapiddetectionofmethicillinresistantStaphylococcifrombloodculturebottlesbyusingamultiplexPCRassay.J.Clin.Microbiol.40:2786-2790.Maes,N.,J.Magdalena,S.Rottieers,Y.DeGheldre,andM.J.Stru...
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心脏移植术后免疫抑制治疗的研究与展望
...，而CsA的1/10～1/100［5］FK506具有强大的抗排斥反应作用。Mathieu等［6］对14例难治性排斥反应和对CsA不能耐受的患者进行FK506治疗，排斥反应的发生率从（0.42±0.17）次/（人·月）降至（0.42±0.09）次/（人·月）。FK506具有与CsA相类...
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AirPollutionandChildRespiratoryHealth
...ompsonS.Quantifyingheterogeneityinameta-analysis.StatMed2002;21:1539eC1558.Mathieu-NolfM.Poisonsintheair:acauseofchronicdiseaseinchildren.JToxicolClinToxicol2002;40:483eC491.KatsouyanniK.Ambientairpollutionandhealth.BrMedBull2003;68:143eC156.ChauhanA,JohnstonS.Airpollutionandinfectioninrespiratoryil...
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PulmonaryBloodFlowHeterogeneityduringHypoxiaandHigh-AltitudePulmonaryEdema
...d-gasbarrierineliteathletes.AmJRespirCritCareMed1997;155:1090eC1094.WestJB,Mathieu-CostelloO,JonesJH,BirksEK,LogemannRB,PascoeJR,TylerWS.Stressfailureofpulmonarycapillariesinracehorseswithexercise-inducedpulmonaryhemorrhage.JApplPhysiol1993;75:1097eC1109.HanaokaM,TanakaM,GeR-L,DromaY,ItoA,MiyaharaT,...
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BloodOxygenLevel–DependentMRIofTissueOxygenation
...aloxygenconsumptionrates.AmJPhysiolHeartCircPhysiol.2003;285:H2382–H2391.Mathieu-CostelloO.Capillarytortuosityanddegreeofcontractionorextensionofskeletalmuscles.MicrovascRes.1987;33:98–117.作者：WolfgangUtz;JensJordan;ThoralfNiendorf;Mandy
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UseofaMultiplexMolecularBeaconPlatformforRapidDetectionofMethicillinandVancomycinResistanceinStaphylococcusaureus
...ficprobesofmecandTn554.Microb.DrugResist.1:307-313.Louie,L.,J.Goodfellow,P.Mathieu,A.Glatt,M.Louie,andA.E.Simor.2002.Rapiddetectionofmethicillin-resistantstaphylococcifrombloodculturebottlesbyusingamultiplexPCRassay.J.Clin.Microbiol.40:2786-2790.Lowy,F.D.1998.Staphylococcusaureusinfections.N.Engl.J....
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哮喘治疗新进展
...在持续的气管炎症，是一个普遍的较难解决的临床问题。Mathieu等表明过度表达GR可解决CS不敏感型哮喘受体表达及功能缺陷的问题。PPAR-γ激动剂具有很高的哮喘治疗潜能。天然的PPAR-γ激动剂如15-脱氧-δ12，14PGJ2（15dPGJ2），是从...
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ContributionofSystematicSerologicalTestinginDiagnosisofInfectiveEndocarditis
...fect.Dis.23:298-302.Hoen,B.,C.Selton-Suty,N.Danchin,M.Weber,J.P.Villemot,P.Mathieu,J.Floquet,andM.Canton.1995.EvaluationoftheDukecriteriaversustheBethIsraelcriteriaforthediagnosisofinfectiveendocarditis.Clin.Infect.Dis.21:905-909.Hoen,B.,C.Selton-Suty,F.Lacassin,J.Etienne,S.Brianon,C.Leport,andP.Can...
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AnalysisoftheComparativeWorkflowandPerformanceCharacteristicsoftheVITEK2andPhoenixSystems
...stingandbacterialidentification.J.Clin.Microbiol.32:1757-1762.Donay,J.L.,D.Mathieu,P.Fernandes,C.Pregermain,P.Bruel,A.Wargnier,I.Casin,F.X.Weill,P.H.Lagrange,andJ.L.Herrmann.2004.EvaluationoftheautomatedPhoenixsystemforpotentialroutineuseintheclinicalmicrobiologylaboratory.J.Clin.Microbiol.42:1542-1...
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RegulationofTCRandrepertoiresbylocalandlong-distancecontrolofvariablegenesegmentchromatinstructure
...combinationduringB-cellontogenyanddevelopment.Mol.Cell.Biol.23:2438–2450.Mathieu,N.,W.M.Hempel,S.Spicuglia,C.Verthuy,andP.Ferrier.2000.ChromatinremodelingbytheTcellreceptor(TCR)–geneenhancerduringearlyTcelldevelopment:implicationsforthecontrolofTCR-locusrecombination.J.Exp.Med.192:625–636.作...
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维生素D的免疫功能及肾脏疾病中的应用
...及VDR转录活性水平高的部位能提高Th0向Th2细胞方向分化。Mathieu等[18]研究非肥胖糖尿病(NOD)鼠发现1,25(OH)2D能使NOD鼠偏移的Th1向Th2细胞方向转化。此外，有人假设1,25(OH)2D可能促进Th0细胞向以细胞免疫为主的Th1分化，该机制提示维生...
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DetectionofHumanImmunodeficiencyVirusType1DNAinDriedBloodSpotsbyaDuplexReal-TimePCRAssay
...irustype1DNA.J.Clin.Microbiol.37:350-353.Roques,P.,D.Marce,C.Courpotin,F.P.Mathieu,F.Herve,F.D.Boussin,R.Narwa,M.C.Meyohas,C.Dollfus,andD.Dormont.1993.CorrelationbetweenHIVprovirusburdenandinuterotransmission.AIDS1993(Suppl.2):S39-S43.Yourno,J.,andJ.Conroy.1992.Anovelpolymerasechainreactionmethodfor...
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一氧化碳中毒及其迟发性脑病
...预后差的最佳临床指标。 ［参考文献］ 1RaubJA，MathieuNolfM，HampsonNB，etal.Carbonmonoxideapublichealthperspective.Toxicology，2000，145：1-14. 2AbelsohnA，SanbornMD，JessimanBJ，etal.Identifyingandmanagingadverseenvironmentalhealtheffects：6.Carbonmono...
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RepetitionofIschemicPreconditioningAugmentsEndothelium-DependentVasodilationinHumans
...edgrowthfactor.ProcNatlAcadSciUSA.1992;89:6138–6141.OlfertIM,BreenEC,Mathieu-CostelloO,WagnerPD.SkeletalmusclecapillarityandangiogenicmRNAlevelsafterexercisetraininginnormoxiaandchronichypoxia.JApplPhysiol.2001;91:1176–1184.GavinTP,RobinsonCB,YeagerRC,EnglandJA,NifongLW,HicknerRC.Angioge...
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AdenoviralGeneTransferofFGF-5toHibernatingMyocardiumImprovesFunctionandStimulatesMyocytestoHypertrophyandReentertheCellCycle
....1995;91:145eC153.GiordanoFJ,PingP,McKirnanMD,NozakiS,DeMariaAN,DillmannWH,Mathieu-CostelloO,HammondHK.Intracoronarygenetransferoffibroblastgrowthfactor-5increasesbloodflowandcontractilefunctioninanischemicregionoftheheart.NatMed.1996;2:534eC539.ShouM,ThirumurtiV,RajanayagamS,LazarousDF,HodgeE,Stibe...
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癌症的转移及其防治对策
...ysActa，2004，1654（1）：3～12. ［7］GrunsteinJ，RobertsWG，Mathieu-CostelloO，etal.Tumor-derivedexpressionofvascularendothelialgrowthfactorisacriticalfactorintumorexpansionandvascularfunction［J］.CancerRes，1999，59（7）：1592～1598. ［8］IshikawaM，KitayamaJ，Kaza...
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中医导引术和印度瑜伽术比较研究
导引是中国古代的一种养生术和治疗术，亦作“道引。导是指“导气令和，引是指“引体令柔。导引通过肢体动作、呼吸吐纳、心理调节达到强身健体、疏通经络、调摄精神的目的。瑜伽源于印度梵语yug或yuj，是“...
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TheCrystalStructureoftheComplexoftheAnticancerProdrug7-Ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin(CPT-11)withTorpedocalifo
...inOncol17:1815eC1824.GandiaD,AbigergesD,ArmandJP,ChabotG,DaCostaL,DeForniM,Mathieu-BoueA,andHeraitP(1993)CPT-11-inducedcholinergiceffectsincancerpatients.JClinOncol11:196eC197.HarelM,KleywegtGJ,RavelliRB,SilmanI,andSussmanJL(1995)Crystalstructureofanacetylcholinesterase-fasciculincomplex:interaction...
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高血压脑出血外科治疗疗效分析
【摘要】目的探讨高血压脑出血外科治疗术式疗效。方法回顾分析320例高血压脑出血病例资料。结果6h内手术组病死率10.2%（10/98），6h后组病死率36%（80/222）。30～59ml组中66例行微创血肿清除术及小骨窗血肿清除术，76例行血肿清...