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VariationoftheConservedNeutralizingEpitopeinInfluenzaBVirusVictoriaGroupIsolatesinJapan
...theevolutionofinfluenzaBvirusesinnature.J.Virol.73:7343-7348.Nakagawa,N.,A.Maeda,T.Kase,R.Kubota,andY.Okuno.1999.RapiddetectionandidentificationoftwolineagesofinfluenzaBstrainswithmonoclonalantibodies.J.Virol.Methods79:113-120.Nakagawa,N.,R.Kubota,A.Maeda,T.Nakagawa,andY.Okuno.2000.Heterogeneityofin...
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2009年度生物燃料最佳公司，BP生物燃料获此殊荣
...，生产生物丁醇。在巴西，BP于2008年与SantelisaVale公司、Maeda集团共同成立了Tropical公司，BP占有50%的股份。 在Tropical公司实现生产的第一年，世界精炼协会将“生物燃料最佳公司”授予BP生物燃料，这是对BP生物燃料成功成长...
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脂肪细胞因子adiponectin的研究进展
...受。Kondo等［12］经广泛基因组扫描发现2型糖尿病和代谢综合征的易感位点在染色体3q27，即是adiponectin基因所在位点。Hara等对adiponectin基因位点45、276的核苷酸多态性与2型糖尿病之间的关系提出了证据，位点45、276是G/G基因型的...
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BP投资10亿在巴西开发生物燃料
...乙醇生产商SantelisaVale集团与全球最大的棉花生产商之一Maeda集团合资组建。据了解，目前它正在巴西Goias州的Edeia市兴建一座年产量为4．35亿升（合1．15亿美加仑）的乙醇生产厂。 此前，BP宣布计划出资购进巴西热带生物能源...
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DistributionofStrainFamiliesofMycobacteriumtuberculosisCausingPulmonaryandExtrapulmonaryDiseaseinHospitalizedChildreninCapeTown,SouthAfrica
...umtuberculosisfordiagnosisandepidemiology.J.Clin.Microbiol.35:907-914.Kato-Maeda,M.,P.J.Bifani,B.N.Kreiswirth,andP.M.Small.2001.ThenatureandconsequenceofgeneticvariabilitywithinMycobacteriumtuberculosis.J.Clin.Investig.107:533-537.Lari,N.,L.Rindi,C.Sola,D.Bonanni,N.Rastogi,E.Tortoli,andC.Garzelli.Ge...
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UseofRapidGenomicDeletionTypingToMonitoraTuberculosisOutbreakwithinanUrbanHomelessPopulation
...losisandtheirhumanhostpopulations.Proc.Natl.Acad.Sci.USA101:4871-4876.Kato-Maeda,M.,J.T.Rhee,T.R.Gingeras,H.Salamon,J.Drenkow,N.Smittipat,andP.M.Small.2001.ComparinggenomeswithinthespeciesMycobacteriumtuberculosis.GenomeRes.11:547-554.Kurepina,N.E.,S.Sreevatsan,B.B.Plikaytis,P.J.Bifani,N.D.Connell,R...
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VEGF、CD34在乳腺癌中的表达研究
...结果判定 1.4.1VEGF表达根据阳性细胞数及染色强度进行综合判定，即按5%以上细胞浆或细胞膜呈棕黄色染色者为VEGF蛋白表达阳性。 1.4.2MVD计数参照Maeda等报道［2］的方法，即低倍镜下，全面观察CD34染色阳性的血管，选取肿...
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EvaluationofUniversalProbesandPrimerSetsforAssessingTotalBacterialLoadinClinicalSamples:GeneralImplicationsandPracticalUseinEndodonticAn
...centageofperfectmatcheswiththeprotocolsusedbyTakaietal.(26),Tsengetal.(27),Maedaetal.(14),andNadkarnietal.(17),withthelastprotocolhavingthehighestscoresforbothPCRamplificationandprobehybridization(i.e.,74%and63%,respectively).However,asisevidentfromTable2,noPCRprotocolincludesalltaxonomicgroups(i.e....
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SimpleMethodforDeterminationoftheNumberofHelicobacterpyloriCagAVariable-RegionEPIYATyrosinePhosphorylationMotifsbyPCR
...14-523.Asahi,M.,T.Azuma,S.Ito,Y.Ito,H.Suto,Y.Nagai,M.Tsubokawa,Y.Tohyama,S.Maeda,M.Omata,T.Suzuki,andC.Sasakawa.2000.HelicobacterpyloriCagAproteincanbetyrosinephosphorylatedingastricepithelialcells.J.Exp.Med.191:593-602.Asahi,M.,Y.Tanaka,T.Izumi,Y.Ito,H.Naiki,D.Kersulyte,K.Tsujikawa,M.Saito,K.Sada,S...
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Contributionofadiposetissueanddenovolipogenesistononalcoholicfattyliverdisease
...licfattyliverdisease.J.Clin.Invest.115::1343-1351.doi:10.1172/JCI200523621.Maeda,N.etal.2002..Diet-inducedinsulinresistanceinmicelackingadiponectin/ACRP30.Nat.Med.8::731-737.Furukawa,S.etal.2004..Increasedoxidativestressinobesityanditsimpactonmetabolicsyndrome.J.Clin.Invest.114::1752-1761.doi:10.117...
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DistributionofInsertion-andDeletion-AssociatedGeneticPolymorphismsamongFourMycobacteriumtuberculosisPhospholipaseCGenesandAssociationswithExt
...aseCandphospholipaseDactivityinmycobacteria.Infect.Immun.64:3259-3266.Kato-Maeda,M.,J.T.Rhee,T.R.Gingeras,H.Salamon,J.Drenkow,N.Smittipat,andP.M.Small.2001.ComparinggenomeswithinthespeciesMycobacteriumtuberculosis.GenomeRes.11:547-554.Liang,K.Y.,andS.Zeger.1986.Longitudinaldataanalysisusinggeneraliz...
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IBkinase(IKK),butnotIKK,isacriticalmediatorofosteoclastsurvivalandisrequiredforinflammation-inducedboneloss
...ebertzandL.KennerforhelpfuldiscussionandA.ChangforLPSkneejointinjections.S.Maeda,J.M.Park,L.-C.Hsu,andY.CaoweresupportedbypostdoctoralfellowshipsfromtheJapanSocietyforthePromotionofScience,Bristol-MyersSquibbFoundationResearchFellowshipattheIrvingtonInstitute,theCancerResearchInstitute,andanAmerican...
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LowConcentrationsofNitricOxideExertaHormeticEffectonMycobacteriumtuberculosisInVitro
...on.Annu.Rev.Pharmacol.43:175-197.Doi,T.,M.Ando,T.Akaike,M.Suga,K.Sato,andH.Maeda.1993.ResistancetonitricoxideinMycobacteriumaviumcomplexanditsimplicationinpathogenesis.Infect.Immun.61:1980-1989.Firmani,M.A.,andL.W.Riley.2002.MycobacteriumtuberculosisCDC1551isresistanttoreactivenitrogenandoxygeninter...
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Immunecomplexesastherapyforautoimmunity
...dependentinvitroandinvivophagocytosisofbloodcells.Br.J.Haematol.127::90-96.Maeda,H.etal.2001..Successfultreatmentof“malignantrheumatoidarthritis“inJapanwithpooledintravenousimmunoglobulin.Rheumatology.40::955-956.DiazdeStahl,T.etal.2002..ExpressionofFcgammaRIIIisrequiredfordevelopmentofcollagen-...
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肿瘤标记物联合检测在非小细胞肺癌化疗中的意义
...水平明显减低的病人,复查CT显示有明显好转。这也印证了MAEDA等[5]的观点。本文CA199水平化疗前后差异无显著性,可能与病例数过少有关，有待扩大样本进行进一步的研究。 综上所述，CEA、CA125、CA50水平下降可评价非小细胞...
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Mycobacteriumaviumsubsp.paratuberculosis,GeneticSusceptibilitytoCrohn‘sDisease,andSardinians:theWayAhead
...D2variantsinJapanesepatientswithCrohn‘sdisease.Gastroenterology123:86-91.Maeda,S.,L.C.Hsu,H.Liu,L.A.Bankston,M.Iimura,M.F.Kagnoff,L.Eckmann,andM.Karin.2005.Nod2mutationinCrohn‘sdiseasepotentiatesNF-kappaBactivityandIL-1betaprocessing.Science307:734-738.Naser,S.A.,G.Ghobrial,C.Romero,andJ.F.Valen...
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Phosphorylationofhistonedeacetylase7byproteinkinaseDmediatesTcellreceptor–inducedNur77expressionandapoptosis
...isregulatedby14-3-3proteins.Mol.Cell.Biol.22:916–926.VanLint,J.,A.Rykx,Y.Maeda,T.Vantus,S.Sturany,V.Malhotra,J.R.Vandenheede,andT.Seufferlein.2002.ProteinkinaseD:anintracellulartrafficregulatoronthemove.TrendsCellBiol.12:193–200.Matthews,S.A.,T.Iglesias,E.Rozengurt,andD.Cantrell.2000.Spatialandt...
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Cetyl-PyridiniumChlorideIsUsefulforIsolationofMycobacteriumtuberculosisfromSputaSubjectedtoLong-TermStorage
...z,3Es,Paris,France.REFERENCESBobadilla-del-Valle,M.,A.Ponce-de-Leon,M.Kato-Maeda,A.Hernandez-Cruz,J.J.Calva-Mercado,B.Chavez-Mazari,B.A.Caballero-Rivera,J.C.Nolasco-Garcia,andJ.Sifuentes-Osornio.2003.Comparisonofsodiumcarbonate,cetyl-pyridiniumchloride,andsodiumborateforpreservationofsputaforculture...
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Non-Culture-BasedAnalysisofBacterialPopulationsfromPatientswithChronicRhinosinusitis
...nceanalysis.Diagn.Microbiol.Infect.Dis.43:193-199.Takao,A.,H.Nagamune,andN.Maeda.2004.IdentificationoftheanginosusgroupwithinthegenusStreptococcususingpolymerasechainreaction.FEMSMicrobiol.Lett.233:83-89.vonWintzingerode,F.,U.B.Gobel,andE.Stackebrandt.1997.Determinationofmicrobialdiversityinenvironm...
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宫颈鳞状细胞癌微血管密度的检测意义
...［4］。微血管密度（MVD）计数统计：参照Veidner等［5］和Maeda等［6］报道的方法，观察FⅧAg因子染色的切片，先在低倍镜（×100）下全面观察切片以确定肿瘤内血管密度最高处（高血管密度区多位于肿瘤边缘），再在高倍镜（×20...
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IKK/NF-Bsignaling:balancinglifeanddeath–anewapproachtocancertherapy
...dsustainedJNKactivationbyinhibitingMAPkinasephosphatases.Cell.120::649-661.Maeda,S.etal.2003..IKKbetaisrequiredforpreventionofapoptosismediatedbycell-boundbutnotbycirculatingTNFalpha.Immunity.19::725-737.Weil,R.,andIsrael,A.2004..T-cell-receptor-andB-cell-receptor-mediatedactivationofNF-kappaBinlymp...
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GenomicAnalysisofMycobacteriumtuberculosisComplexStrainsUsedforProductionofPurifiedProteinDerivative
...cobacteriumtuberculosiscomplex.Microbiology145:1695-1701.Salamon,H.,M.Kato-Maeda,P.M.Small,J.Drenkow,andT.R.Gingeras.2000.DetectionofdeletedgenomicDNAusingasemiautomatedcomputationalanalysisofGeneChipdata.GenomeRes.10:2044-2054.Seibert,F.B.,andJ.T.Glenn.1941.Tuberculinpurifiedproteinderivative:prepa...
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子宫内膜癌血管内皮生长因子及微血管密度表达的研究
...-）；3~4为弱阳性（+）；5~6为强阳性（++）。MVD计数参照Maeda等［3］和Veidner等［4］报道的方法，由两个对患者情况不了解的医生背对背分别计数，取其平均值。先在低倍镜（×100）下全面观察切片以确定肿瘤内血管密度最高处，...
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AnalysisofGenomicDownsizingontheBasisofRegion-of-DifferencePolymorphismProfilingofMycobacteriumtuberculosisPatientIsolatesRevealsGeographicP
...losisandtheirhumanhostpopulations.Proc.Natl.Acad.Sci.USA101:4871-4876.Kato-Maeda,M.,J.T.Rhee,T.R.Gingeras,H.Salamon,J.Drenkow,N.Smittipat,andP.M.Small.2001.ComparinggenomeswithinthespeciesMycobacteriumtuberculosis.GenomeRes.11:547-554.Kox,L.F.,J.vanLeeuwen,S.Knijper,H.M.Jansen,andA.H.Kolk.1995.PCRas...
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babA2-andcagA-PositiveHelicobacterpyloriStrainsAreAssociatedwithDuodenalUlcerandGastricCarcinomainBrazil
...veHelicobacterpyloriclinicalisolatesinTaiwan.J.Clin.Microbiol.40:3860-3862.Maeda,S.,K.Ogura,H.Yoshida,F.Kanai,T.Ikenoue,N.Kato,Y.Shiratori,andM.Omata.1998.Majorfactors,VacAandCagA,arecommonlypositiveinHelicobacterpyloriisolatesinJapan.Gut42:338-343.Mizushima,T.,T.Sugiyama,Y.Komatsu,J.Ishizuka,M.Kato...
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HLA基因分型方法研究进展
...CODES公司开发出的HLA基因分型技术［9］，也称为序列微珠综合分析实验系统，它利用传统PCR-SSOP的原理，样品首先进行非特异性扩增。扩增产物经解链后与包被了特异性HLADNA探针的微珠结合，在一种专用流氏细胞仪中检测，这种...
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InteractionofCagAwithCrkplaysanimportantroleinHelicobacterpylori–inducedlossofgastricepithelialcelladhesion
...–466.Asahi,M.,T.Azuma,S.Ito,Y.Ito,H.Suto,Y.Nagai,M.Tsubokawa,Y.Tohyama,S.Maeda,M.Omata,etal.2000.HelicobacterpyloriCagAproteincanbetyrosinephosphorylatedingastricepithelialcells.J.Exp.Med.191:593–602.Odenbreit,S.,J.Puls,B.Sedlmaier,E.Gerland,W.Fischer,andR.Haas.2000.TranslocationofHelicobacterpy...
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UseoftheGenomicSubtractiveHybridizationTechniqueToDevelopaReal-TimePCRAssayforQuantitativeDetectionofPrevotellaspp.inOralBiofilmSamples
...icrobiol.42:2255-2257.Tanaka,M.,Y.Yamamoto,M.Kuboniwa,A.Nonaka,N.Nishida,K.Maeda,K.Kataoka,H.Nagata,andS.Shizukuishi.2004.Contributionofperiodontalpathogensontonguedorsaanalyzedwithreal-timePCRtooralmalodor.MicrobesInfect.6:1078-1083.vanSteenbergen,T.J.,C.J.Bosch-Tijhof,M.D.Petit,andU.VanderVelden.1...
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RecruitmentofGr-1+monocytesisessentialforcontrolofacutetoxoplasmosis
...01–608.Kuziel,W.A.,S.J.Morgan,T.C.Dawson,S.Griffin,O.Smithies,K.Ley,andN.Maeda.1997.SeverereductioninleukocyteadhesionandmonocyteextravasationinmicedeficientinCCchemokinereceptor2.Proc.Natl.Acad.Sci.USA.94:12053–12058.Serbina,N.V.,T.P.Salazar-Mather,C.A.Biron,W.A.Kuziel,andE.G.P.Am.2003.TNF/iNOS...
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ClinicalRelevanceofthevacA,iceA,cagA,andflaAGenesofHelicobacterpyloriStrainsIsolatedinEasternTaiwan
...nfectionswithmultiplestrains.Scand.J.Gastroenterol.36:128-135.Ikenoue,T.,S.Maeda,K.Ogura,M.Akanuma,Y.Mitsuno,Y.Imai,H.Yoshida,Y.Shiratori,andM.Omata.2001.DeterminationofHelicobacterpylorivirulencebysimplegeneanalysisofthecagpathogenicityisland.Clin.Diagn.Lab.Immunol.8:181-186.Kim,S.-Y.,C.W.Woo,Y.-M....