-
附属肿瘤医院V—MAT开机庆典隆重举行
...花与微笑，共同庆祝亚洲首台容积弧形调强放射治疗机V-MAT落户我院。9点58分，V-MAT开机庆典在外科楼门前正式举行。黑龙江省委常委、秘书长刘国中，黑龙江省人大常委会副主任申立国，黑龙江省政协副主席、省委统战部部长...
-
附属肿瘤医院引入国际最新容积弧形调强放射治疗机V-MAT
...水准的放射治疗设备系统——容积弧形调强放射治疗机V-MAT（威麦特）。日前，这套亚洲首套系统已落户到哈医大附属肿瘤医院，为今后肿瘤放射治疗提供了强大的设备支撑和技术保证。放射治疗作为肿瘤治疗的三大手段之一，...
-
苦参碱对大鼠原代培养皮质神经元GABAR蛋白表达的影响*
...增强。【关键词】苦参碱;神经元；γ-氨基丁酸受体EffectofmatrineontheexpressionofGABARontheneuronsinpostnatalratcortexincultureLIUTing，YUJian-qiang.DeptofPharmacology,NingxiaMedColl,Yinchuan750004,China【Abstract】ObjectiveTostudythemechanismoftheinbitoryeffectofmatrineoncentra...
-
ImportanceofadeficiencyinS-adenosyl-L-methioninesynthesisinthepathogenesisofliverinjury
...e;nez-Chantar,ElenaRGarcía-Trevijano,MUjueLatasa,IsabelPérez-Mato,ManuelMSánchezdelPino,FernandoJCorrales,MatiasAAvilaandJoséMMato1FromtheDivisionofHepatologyandGeneTherapy,SchoolofMedicine,UniversityofNavarra,Pamplona,Spain.2PresentedatthesymposiumS-Adenosylmethionine(SA...
-
冯慧云综述论文在《材料科学与工程研究报告》发表
《材料科学与工程研究报告》(MaterialsScienceandEngineering:R:Reports)是材料科学与工程领域的顶级刊物，专门发表在材料与工程学科领域具有较高影响和造诣的著名专家撰写的文献综述类论文，对相关领域的发展具有重要的引领和指导...
-
再次麻疹的发病特点和免疫学机制
...。据临床表现分典型（TY）、轻型典型(MT)及轻型非典型(MAT)3型。用ELISA法检测患者急性期及25名有麻疹病史的麻疹密切接触者血清抗-麻疹病毒（MV）IgM、IgG和抗-风疹病毒IgM。结果36例再次麻疹患者年龄12.5～27（16.1）岁，以13～16岁...
-
淀粉样蛋白前体蛋白抑制神经递质的生成
...选蛋白引起了我们的注意，这就是蛋氨酸腺苷酶II，简称MAT2A。研究发现这种酶是神经递质生成的关键。低APP的细胞含有比正常量的APP细胞较少的MAT2A。为了确认“老年痴呆症蛋白质”APP和神经递质MAT2A之间的联系，该研究小组利...
-
Mousemodelofinduciblenephrogenicdiabetesinsipidusproducedbyfloxedaquaporin-2genedeletion
...ntrons1and2inthemouseAQP2genebyhomologousrecombinationinembryonicstemcells.Matingofgerm-lineAQP2-loxPmicewithtamoxifen-inducibleCre-expressingmiceproducedoffspringwithinduciblehomozygousCre-AQP2-loxP,whichhadanormalphenotype.Tamoxifeninjectionsover10daysresultedinAQP2geneexcision,withundetectable95%...
-
Proximaltubulewatertransport-lessonsfromaquaporinknockoutmice
...phate,80%ofthefilteredbicarbonate,and60%ofthefilteredsodiumchloride.Approximately70%ofthefilteredwaterisalsoreabsorbedbythissegment.Despitetheseveryhighratesofproximaltubulesolutetransport,theosmolalityoftheluminalfluiddecreasesbyonly5mosmol/kgH2OfromBowman‘sspacetotheendoftheproximaltubuleaccessi...
-
MultiplexPCRforTypingStrainsofToxoplasmagondii
...location(6).Inimmunocompetentchildrenandadults,theinfectionisusuallyasymptomaticorrevealedin10%ofcasesbycervicaloroccipitallymphadenopathy(14).However,muchlessfrequently,inimmunocompetentindividualssevereacquiredforms,suchaschorioretinitis(3),orpulmonaryforms(4)havealsobeendescribed.Whenacquiredcong...
-
阵发性室上性心动过速治疗体会
...3)触发激动包括房速伴房室传导阻滞、多源房性心动过速(MAT)。以上各类型室上速均具有折返性心动过速的临床特点：发作与终止表现为突然开始和突然终止，持续时间长短不定。症状包括心悸、头晕、晕厥、心绞痛等，严重时...
-
RoleofS-adenosylmethionine,folate,andbetaineinthetreatmentofalcoholicliverdisease:summaryofasymposium
...oxidativestressthroughtheup-regulationofglutathionesynthesis,reducinginflammationviathedown-regulationoftumornecrosisfactor-andtheup-regulationofinterleukin-10synthesis,increasingtheratioofSAMtoS-adenosylhomocysteine(SAH),andinhibitingtheapoptosisofnormalhepatocytesandstimulatingtheapoptosisofliverc...
-
钩端螺旋体疏水外膜蛋白(OmpL39)对豚鼠免疫功能影响的研究
...分析。结果 OmpL39在豚鼠体内能产生高效价的显凝抗体(MAT：1∶3200)。RBC-C3bRR、RBC-ICR均明显升高(P＜0.05)；红细胞免疫粘附因子促进率(RFER)上升，抑制率(RFIR)下降，两者比值显著增大(P＜0.05)。结论 OmpL39对豚鼠有有效的免疫保护...
-
Effectsofmelatoninonthenitricoxidetreatedretina
...meaninnerretinallayerthickness(mIRLT),thenumberofretinasexpressinghyperchromatic(HC)nucleiintheinnernuclearlayer(INL)andtheapoptoticganglioncelldetectionwerecompared.Results:After1day,SNPsignificantlyincreasedthemIRLTby45%(p=0.004),initiatedmoreINLnuclearHCexpression(p=0.01)andapoptoticnuclei(p0.05)...
-
MembraneorganizationandfunctionofM1andM23isoformsofaquaporin-4inepithelialcells
...lines,suggestingthatsingle-channelpf(cm3/s)ismuchgreaterfortheM23variant.SomaticfusionofM1-andM23-AQP4cells(Pf=0.028cm/s)yieldedOAPsthatwerefewerandsmallerthaninM23cellsalone,andM1-to-M23expressionratios(1:4)normalizedtoAQP4inM1orM23cellsindicatedareducedsingle-channelpffortheM23variant.Expressionof...
-
包头地区服务行业人群嗜肺军团菌（1～10型）感染状况调查
...菌（1～10型）自然感染状况。方法采用微量凝集试验法（MAT）对包头地区服务行业732名健康人员进行了嗜肺军团菌（1～10型）感染状况的调查。结果嗜肺军团菌抗体阳性率为3.69%～27.05%，其中Lp6最高（27.05%），其次为Lp5（17.62%）...
-
TemporalProfilesofAxonTerminals,SynapsesandSpinesintheIschemicPenumbraoftheCerebralCortex
...byfocusingonthetemporalprofilesofaxonterminals,synapses,spines,andneurites.MaterialsandMethodsUnderanesthesiawith2%halothane,70%nitrousoxide,and30%oxygen,theleftcarotidarteryofadultmaleMongoliangerbils(60to80g)wastwiceoccludedwithaHeifetzaneurismalclipfor10minuteseachtime,witha5-hourintervalbetweent...
-
DefectivewaterandglyceroltransportintheproximaltubulesofAQP7knockoutmice
...ycerolcouldbeanewmarkerfortheinvivodetectionofproximalstraighttubuleinjury.MATERIALSANDMETHODSGenerationofAQP7knockoutmice.ThemousegenomicclonescontainingtheAQP7genewereisolatedfromamousegenomiclibrary(Stratagene)byplaquehybridizationusingmouseAQP7cDNAasaprobe.AsshowninFig.1A,theconstructwasdesigned...
-
Consumptionoffat-freefluidmilkafterresistanceexercisepromotesgreaterleanmassaccretionthandoesconsumptionofsoyorcarbohydrateinyoung,novic
...ndPediatricsandMedicine,McMasterUniversityMedicalCentre,Hamilton,ON,Canada(MAT)2SupportedbyagrantfromtheUSNationalDairyCouncil(SMP),aCanadianInstitutesforHealthResearch(CIHR)master‘sgraduateaward(JET),andaCIHRCanadaGraduateScholarship(SBW).SMPreceivedaCIHRNewInvestigatoraward.3Reprintsnotavailable...
-
湖南钩端螺旋体病高发区不同年龄村民免疫水平解析
...高峰前采取静脉血，按国家标准方法即显微镜凝集试验（MAT）测15群15型钩体抗体；用SPSSV10.0forWindows统计软件进行数据分析。结果人群检出15个群抗体，除2个群分别有1例阳性外，13个群各年龄组的抗体阳性（滴度在1:20至80）和隐...
-
巨噬细胞是肾移植物动脉内膜炎的主要炎症细胞
...般认为动脉炎是由淋巴细胞引起的。新西兰惠灵顿医院的Mat作者：自动采集
-
［3H］-洛非西定在大鼠的绝对生物利用度
...61149.34±322.70806.01±201.44MRT/h7.09±1.328.77±2.106.64±1.258.43±1.97MAT/h 1.69 1.79F/% 54.0 54.7 iv组或po组的参数AUC/X00.05),表明在本实验所用剂量范围内为线性动力学过程；两剂量组［3H］-LOF的绝对生物利用度相近,分别为54.0%和54.7%。平...
-
［3H］-洛非西定在大鼠的绝对生物利用度
...61149.34±322.70806.01±201.44MRT/h7.09±1.328.77±2.106.64±1.258.43±1.97MAT/h 1.69 1.79F/% 54.0 54.7 iv组或po组的参数AUC/X00.05),表明在本实验所用剂量范围内为线性动力学过程；两剂量组［3H］-LOF的绝对生物利用度相近,分别为54.0%和54.7%。平...
-
Renalmedullarygeneexpressioninaquaporin-1nullmice
...tionbetweenthewild-typeandknockoutgroups.Werandomlyselected35genesforconfirmationbyreal-timePCR,and29ofthe35geneswereconfirmedusingthismethod.TheoverallpatternofgeneexpressionintheAQP1nullmicewasoneofdownregulationcomparedwithgeneexpressionintherenalmedullasofthewild-typemice.Heatshockproteins105and...
-
杰出女科学家安妮·德让-阿瑟马：科学需要女性
...国巴斯德研究所女教授安妮·德让-阿瑟马（AnneDejean-Assémat），以褒奖她为揭示人类肿瘤分子与细胞构成作出的贡献。自2003年起，安妮就领导巴斯德研究所的细胞核组织与肿瘤形成组织研究小组和法国国家健康与医学研究院（Inse...
-
兰州地区健康人群军团菌感染状况调查
...）共357份，老年组（60岁以上）176份。采用微量凝集法（MAT）进行Lp1～14、Lm共两种15型的抗体滴度检测。稀释抗原使浓度为10亿菌/ml，为便于结果观察，用亚甲蓝染色，每份标本均设阳性及阴性对照，以凝集结果呈的最高血清...
-
FXYDproteins:newregulatorsofNa-K-ATPase
...embersofthisfamily,FXYD1(phospholemman),FXYD2(-subunitofNa-K-ATPase),FXYD3(Mat-8),FXYD4(CHIF),andFXYD7,areauxiliarysubunitsofNa-K-ATPaseandregulateNa-K-ATPaseactivityinatissue-andisoform-specificway.TheseresultshighlightthecomplexityoftheregulationofNa+andK+handlingbyNa-K-ATPase,whichisnecessarytoen...
-
心电图
...atrialfibrillation);Af多源性心房頻脈（multifocalatrialtachycardia);MAT陣發性心房頻脈（paroxysmalatrialtachycardia);PATPSVT規則速率：150-250次/minAF規則,鋸齒狀（2:13:14:1)心房速率：250-350次/分Af不規則心房速率：350-500次/min凹凸不平的基準線,又稱...
-
MutantFibrinogenClearedfromtheEndoplasmicReticulumviaEndoplasmicReticulum-AssociatedProteinDegradationandAutophagy
...plasmaproteinsynthesizedinhepatocytes,playsacriticalroleinbloodcoagulation.Maturecirculatingfibrinogenisasymmetricdimericmoleculeinwhicheachhalfconsistsofthreepolypeptidechains:A,Bß,and.ThetwohalvesofthemoleculeassociateintoatrinodalD-E-DstructurewiththeNterminiofallsixchainsinthecentralEdomai...
-
湖南钩端螺旋体病原高发区两时段人群感染状况探析
...，于流行高峰前采静脉血，按国标即做显微镜凝集试验（MAT）测15群15型钩体抗体。结果除巴达维亚群和塔拉索夫群分别只一人有抗体外，其余13个群分别有1.53%～34.35%的人有抗体；近期与前期分别有66.10%和51.75%的人有交叉抗体，...