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加拿大找到抵御病毒侵袭新方法
...毒繁殖的能力。而1型干扰素又受到干扰素调节蛋白质7（lrf7）的控制，研究人员认为lrf7是体内干扰素生产的主要调节器。麦吉尔大学的研究人员发现，lrf7的蛋白合成受到被称为4E-BP1和4E-BP2两种抑制基因的控制。 实验中，科...
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DifferentialEffectsofGq,G14,andG15onVascularSmoothMuscleCellSurvivalandGeneExpressionProfiles
...-synthesisormediateTNF-signalingincludeactivatingtranscriptionfactor3(Atf3/LRF1),acAMPresponseelement-bindingprotein-likenucleartranscriptionfactor,theTGF--likecytokinebonemorphogenicprotein2(BMP2),mitogen-activatedproteinkinasekinasekinase8(Map3K8;Tpl2;Cot),thenucleartranscriptionfactorNGFI-B/Nurr7...
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榄香烯联合生物大分子合成抑制剂对Hca-F肝癌的作用
...特异的，如肝特异转录因子HNF-6转录增加，肝再生因子（LRF）的基因表达下降，细胞周期调控因子CDC25Hu2的基因表达降低，凋亡相关分子BBC3、TRIP的基因表达下降等，采用RT-PCR方法验证了BBC3和TRIP基因的变化［6］。本实验在上述研...
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EvaluationofaModifiedSingle-EnzymeAmplified-FragmentLengthPolymorphismTechniqueforFingerprintingandDifferentiatingofMycobacteriumkansasiiType
...worldwide.Moreover,largerestrictionfragment-pulsed-fieldgelelectrophoresis(LRF-PFGE)(2,14,23),amplified-fragmentlengthpolymorphism(AFLP)analysis(23),andrandomlyamplifiedpolymorphicDNAanalysis(2)haveproducedpolymorphicpatternswithineachtype.Byuseofthesetypingmethods,minimalgeneticpolymorphismwasnoted...
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CocultureofTHP-1HumanMononuclearCellswithCandidaalbicansResultsinPronouncedChangesinHostGeneExpression
...icle28.NawaT,NawaMT,AdachiMT,etal.ExpressionoftranscriptionalrepressorATF3/LRF1inhumanatherosclerosis:colocalizationandpossibleinvolvementincelldeathofvascularendothelialcells.Atherosclerosis2002;161:28191.Firstcitationinarticle29.HesserBA,LiangXH,CamenischG,etal.Downsyndromecriticalregionprotein1(D...