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安美汀中高分子杂质的分离分析与质量控制
...定了以TSK2500PWXL凝胶分离系统，采用对高分子杂质总量（Kav<0.3）和分子量最大的杂质量（Kav<0.1）进行联合控制的质控方法，其检测指标依据临床免皮试研究用样品的高分子杂质的检验结果而制订。结论：方法简便，结果可靠，...
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注射用头孢唑林钠中高分子杂质的检查法
...exG-10凝胶色谱系统中的色谱行为和高分子杂质一样，都在Kav=0处表现为单一的色谱峰，可精确对高分子杂质峰进行定量。结论方法简便，结果可靠。关键词：注射用头孢唑林钠；高分子杂质；凝胶色谱头孢唑林钠适用于治疗敏感...
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凝胶色谱法测定头孢替唑钠的聚合物
...合物在PharmadexG-10凝胶色谱系统中和高分子杂质一样,都在Kav=0处表现为单一的色谱峰的特点,本文用自身对照外标法对聚合物峰进行定量。参考文献〔1〕艾则孜·木哈买提,等1高效液相色谱法测定头孢唑啉钠的聚合物〔J〕1中国抗生...
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凝胶色谱法测定头孢替唑钠的聚合物
...合物在PharmadexG-10凝胶色谱系统中和高分子杂质一样,都在Kav=0处表现为单一的色谱峰的特点,本文用自身对照外标法对聚合物峰进行定量。参考文献〔1〕艾则孜·木哈买提,等1高效液相色谱法测定头孢唑啉钠的聚合物〔J〕1中国抗生...
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TwonovelmutationsofconnexingenesinChinesefamilieswithautosomaldominantcongenitalnuclearcataract
...pandthegeneticandphenotypicheterogeneityofcataract.ReferencesLambertSL,DrackAV.Infantilecataracts.SurvOphthalmol1996;40:427–58.WhiteTW.Uniqueandredundantconnexincontributionstolensdevelopment.Science2002;295:319–20.ShielsA,MackayD,IonidesA,etal.Amissensemutationinthehumanconnexin50gene(GJA8)unde...
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生化实验讲义(理论部分)三－－层析技术（一）
...子量测定前面已经介绍了，在一定的范围内，各个组分的Kav以及Ve与其分子量的对数成线性关系。Kav＝－blgMW＋cVe＝－b’lgMW＋c’由此通过对已知分子量的标准物质进行洗脱，作出Ve或Kav对分子量对数的标准曲线，然后在相同的条...
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TheRoleofHyaluronanSynthase3inVentilator-inducedLungInjury
...Vt)wasmeasuredusinguronicacid.HAsizesweredeterminedbyrelativeelutionvolume(Kav)comparedwiththreeHAstandardsofknownmolecularweight(SigmaChemicalCo.andBiomatrix,Inc.,Ridgefield,NJ).Kavwascalculatedfromthefollowingequation:Kav=(elutionvolumeeCVo)/(VteCVo).ThethreeHAstandards,1,600kDHMWHA,370kDLMWHA,and...
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Alternate-dayfastingandchronicdiseaseprevention:areviewofhumanandanimaltrials
...eeringResearchCouncilofCanada.3Reprintsnotavailable.AddresscorrespondencetoKAVarady,DepartmentofNutritionalSciencesandToxicology,UniversityofCalifornia,Berkeley,MorganHall,Room308,Berkeley,CA94720-3104.E-mail:kvarady{at}nature.berkeley.edu.ABSTRACTCalorierestriction(CR)andalternate-dayfasting(ADF)re...
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Plantsterolsandendurancetrainingcombinetofavorablyalterplasmalipidprofilesinpreviouslysedentaryhypercholesterolemicadultsafter8wk
...on,FacultyofAgriculturalandEnvironmentalSciences,McGillUniversity,Montreal(KAV,NE,CAV,andPJHJ),andtheVeterans‘Hospital,SainteAnnedeBellevue,Quebec(WEP)2SupportedbytheHeartandStrokeFoundationofCanada.3AddressreprintrequeststoPJHJones,SchoolofDieteticsandHumanNutrition,McGillUniversity,21,111Lakesho...
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IncreasedglomerularpermeabilitytonegativelychargedFicollrelativetoneutralFicollinrats
...uedextran(2x106Da)andglycine(75Da),respectively.Thedistributioncoefficient(Kav)wasplottedagainstthelogoftheSEradiioftherespectivestandardmoleculesandfittedtoathird-orderpolynomial(Fig.1).Representativemolecularsizedistributioncurvesfromserumandurine(urinewasrecalculatedtoobtainBowman‘sspaceconcent...