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第四节 胃肠道粘膜T淋巴细胞
...）主要包括肠系膜淋巴结和粘膜中集合和散在淋巴滤泡。GALTT淋巴细胞多们于生发中心的外周部位，约占40%。其中CD8和CD4阳细胞比例与周围血相似。动物研究证明，肠系膜淋巴结内的CD4阳民生细胞多于固有层。分子生物学研究发...
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ProgressiveTransformingGrowthFactor1eCinducedLungFibrosisIsBlockedbyanOrallyActiveALK5KinaseInhibitor
...ductionpathwaysleadingtofibrogenesisChest2001;120:43SeC47S.BonniaudP,KolbM,GaltT,RobertsonJ,RobbinsC,StampfliM,LaveryC,MargettsPJ,RobertsAB,GauldieJ.Smad3nullmicedevelopairspaceenlargementandareresistanttoTGF-beta-mediatedpulmonaryfibrosis.JImmunol2004;173:2099eC2108.BonniaudP,MargettsPJ,KolbM,Kapou...
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Thetransportbarrierinintraperitonealtherapy
...delofperitonealdialysisinrats.JAmSocNephrol13:721728,2002.MargettsPJ,KolbM,GaltT,HoffCM,ShockleyTR,andGauldieJ.Genetransferoftransforminggrowthfactor-1totheratperitoneum:effectsonmembranefunction.JAmSocNephrol12:20292039,2001.MarkmanM.Intraperitonealtherapyofovariancarcinoma.SeminOncol25:356360,1998...
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DexamethasoneInducesConnectiveTissueGrowthFactorExpressioninRenalTubularEpithelialCellsinaMouseStrain-SpecificManner
...enalabnormalitiesinlupusnephritis.NEnglJMed1984,311:491-495KolbM,BonniaudP,GaltT,SimePJ,KellyMM,MargettsPJ,GauldieJ:Differencesinthefibrogenicresponseaftertransferofactivetransforminggrowthfactor-ß1genetolungsof“fibrosis-prone“and“fibrosis-resistant“mousestrains.AmJRespirCellMolBiol200...
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vßIntegrinRegulatesRenalFibrosisandInflammationinAlportMouse
...LK5inhibitioninrenaldisease.CurrOpinPharmacol2003,3:204-208BonniaudP,KolbM,GaltT,RobertsonJ,RobbinsC,StampfliM,LaveryC,MargettsPJ,RobertsAB,GauldieJ:Smad3nullmicedevelopairspaceenlargementandareresistanttoTGF-beta-mediatedpulmonaryfibrosis.JImmunol2004,173:2099-2108InazakiK,KanamaruY,KojimaY,Sueyosh...