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HelicobacterPyloriInfectionCausesPersistentPlateletActivationInVivoThroughEnhancedLipidPeroxidation
...ninmiceandhumanHelicobacterpyloriinfection.JClinInvest.1997;100:996–1005.DavìG,FalcoA,PatronoC.DeterminantsofF2-isoprostanebiosynthesisandinhibitioninman.ChemPhysLipids.2004;128:149–163.MorrowJD,HillKE,BurkRF,NammourTM,BadrKF,RobertsLJII.AseriesofprostaglandinF2-likecompoundsareproducedinvivoin...
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“复旦Ⅰ号”心智机器人亮相
...翁博士在美国密西根州立大学先后研制成功“SAIL”和“Dav”机器人。和其他机器人相比，“复旦一号”显得比较粗大，但它的“内心”其实非常细腻。就像一个婴孩可以慢慢认识自己生活的环境，“复旦一号”也可以通过体内...
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Linksbetweenfoodandvasculardisease
JohnCRutledge1FromtheUniversityofCalifornia,Davis,MedicalCenter,theDivisionofEndocrinology,ClinicalNutritionandVascularMedicine,Sacramento.Seecorrespondingarticleonpage119.2Reprintsnotavailable.AddresscorrespondencetoJCRutledge,UniversityofCalifornia,Davis,MedicalCenter,DivisionofEndocrinology,Clini...
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MarkersofInflammationandInfectionInfluencetheOutcomeofPatientsWithBaselineAsymptomaticCarotidLesions
...andatherosclerosis.Stroke.2003;34:333–334.NovoS,BasiliS,TantilloR,FalcoA,DavìV,NovoG,CorradoE,DavìG.SolubleCD40Landcardiovascularriskinasymptomaticcarotidplaque.Stroke.2005;36:673–675.MehtaJL,RomeoF.Inflammation,infectionandatherosclerosis:doantibacterialhavearoleinthetherapyofcoronaryarterydi...
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高阻隔药品包材之阻氧检测技术介绍
...00cc／m2／d9y／0．0005—28000cc／lOOin2/day;水汽002一1000g／m2／daV／0．0002—64.5g/lOOin2／day)，还可模拟包装物储存的各类自然环境进行测试，可进行结果校对，而且测试时间相对较短。2电量分析传感器法的阻氧检测步骤3医药品的安全...
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InterrelationshipbetweenPolymorphismsofincA,FusogenicPropertiesofChlamydiatrachomatisStrains,andClinicalManifestationsinPatientsinTheNetherl
...arathe,L.Aravind,W.Mitchell,L.Olinger,R.L.Tatusov,Q.Zhao,E.V.Koonin,andR.W.Davis.1998.Genomesequenceofanobligateintracellularpathogenofhumans:Chlamydiatrachomatis.Science282:754-759.Suchland,R.J.,D.D.Rockey,J.P.Bannantine,andW.E.Stamm.2000.IsolatesofChlamydiatrachomatisthatoccupynonfusogenicinclusio...
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恶性黑色素瘤
...高有效率，减低毒性反应，常用的联合化疗方案如下：(1)DAV方案(DTIc、ACNu、VCR)为黑色素瘤的首选化疗方案。用药方法：DTIcloo～200mg，ivd1～5ACNUl00mgivd1VCR2mgivd1，每21天重复1次。(2)DDBT方案(DTIC、DDP、BCNU、TAM)用法：DTIC220mg／m2，静注...
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AbsorptionofironfromrecombinanthumanlactoferrininyoungUSwomen
...erdal1andAnnikaBryant11FromtheDepartmentofNutrition,UniversityofCalifornia,Davis,CA2SupportedbyBioSTARgrantno.S99-40fromtheUniversityofCalifornia;VentriaBiosciencedonatedthehumanrecombinantlactoferrinusedinthestudy.3Reprintsnotavailable.AddresscorrespondencetoBLönnerdal,DepartmentofNutrition,Un...
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UseandEffectivenessofWarfarininMedicareBeneficiariesWithAtrialFibrillation
...JAMA.2002;288:2441–2448.作者：ElenaBirman-Deych,MS;MarthaJ.Radford,MD;Dav
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Ironinferritinorinsalts(ferroussulfate)isequallybioavailableinnonanemicwomen
PenniDavila-Hicks,ElizabethCTheilandBoLönnerdal1FromtheDepartmentofNutrition,UniversityofCalifornia,Davis,CA(PD-HandBL),andtheCenterforBioIronatChildren‘sHospitalOaklandResearchInstitute,Oakland,CA(ECT).2SupportedbyNIHgrantHL56961(toPD-H,BL,andECT)andtheCHORIFoundation(ECT).3Reprintsnotavaila...
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硫代反义寡核苷酸体外对HDV的抑制作用
...erHDV/HBV-infection.SecretionofhDAgreachedsummitfromday4today12intertion．Dav2afterS-ASODN(2、4、6μmol/L)wasaddedintothemediumofhepatoeytes,HDVRNAwasinhibited，SecretionofHDAginthesupernantwasreduced．Inhibitoryrateshowedthefeatureofdosagedependence．Conclusionprimaryhumanfe-talhepatocyteisco...
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Responsivenessofdark-adaptationthresholdtovitaminAandß-carotenesupplementationinpregnantandlactatingwomeninNepal
...chardCNavitsky,AnaMSanchez,LeeSFWu,SubarnaKKhatry,MakarDThapa,JeanHumphrey,DavidHazelwoodandKeithPWest,Jr1FromtheCenterforHumanNutrition,DepartmentofInternationalHealth,TheJohnsHopkinsSchoolofHygieneandPublicHealth,Baltimore,andtheNepalSocietyforthePreventionofBlindness,Kathmandu,Nepal.2SupportedbyC...
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Possibleaxonalregrowthinlaterecoveryfromtheminimallyconsciousstate
...ofwhitematterreorganization.(A)Histogramofaverageapparentdiffusionconstant(Dav)ofpatient1(boldline)andthe20normalcontrolsubjectsoverallvoxelsinthebrain.ThehistogramofthepatientshowsanenlargedcompartmentofCSFascomparedwithnormalsubjects.(B)SameasAfortheFA.Thepatient’shistogramlackslargeFAvalues,cha...
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RoleofOsteoprotegerininArterialCalcification
...nettL,BooneT,ShimamotoG,DeRoseM,ElliottR,ColomberoA,TanHL,TrailG,SullivanJ,DavyE,BucayN,Renshaw-GeggL,HughesTM,HillD,PattisonW,CampbellP,SanderS,VanG,TarpleyJ,DerbyP,LeeR,BoyleWJ.Osteoprotegerin:anovelsecretedproteininvolvedintheregulationofbonedensity.Cell.1997;89:309–319.TsudaE,GotoM,Mochizu...
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Lutein,zeaxanthin,macularpigment,andvisualfunctioninadultcysticfibrosispatients
...dInternalMedicine(EO-M,BMM,andCEC),SchoolofMedicine,UniversityofCalifornia,Davis.2SupportedbytheCysticFibrosisFoundation,Hoffmann-LaRocheInc,theNationalInstituteonAging(AG04058),theResearchtoPreventBlindnessJulesandDorisSteinProfessorship,Klee-Stiftung,FrankfurtaM,andtheStudienstiftungdesdeutschenVo...
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UseofResequencingOligonucleotideMicroarraysforIdentificationofStreptococcuspyogenesandAssociatedAntibioticResistanceDeterminants
...icalCenter),JerryDiao(USAF/SGR[Ctr]),RussellP.Kruzelock(VirginiaTech[IPA]),DavidA.Stenger(NavalResearchLaboratory),andElizabethA.Walter(TexasAMUniversitySystemsSanAntonio[IPA]);(iv)technicaladvisorsandcollaboratinginvestigators,LukeDaum(AirForceInstituteforOperationalHealth),DavidMetzgar(NavyHealthR...
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IsolationandCharacterizationofVasohibin-2asaHomologueofVEGF-InducibleEndothelium-DerivedAngiogenesisInhibitorVasohibin
...tedhumanumbilicalveinendothelialcells.Angiogenesis.2001;4:289-298.FerraraN,Davis-SmythT.Thebiologyofvascularendothelialgrowthfactor.EndocrRev.1997;18:4-25.NeufeldG,CohenT,GengrinovitchS,PoltorakZ.Vascularendothelialgrowthfactor(VEGF)anditsreceptors.FasebJ.1999;13:9-22.MakinenT,OlofssonB,KarpanenT,He...
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NeedsandOpportunitiesforResearchinHypersensitivityPneumonitis
...toidentifypossiblecausesofdiseaseandtoprovideappropriateadviceontreatmentandavoidance(24,25).Reactivelowmolecularweightchemicals,manyofwhichareknowncausesofOA,mayactashaptens(protein-freesubstancesthat,whencoupledwithacarrierprotein,elicitanimmuneresponse)wheninhaled,perhapscausingsensitizationandHP...
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ReductionofAtheroscleroticPlaquesbyLysosomalAcidLipaseSupplementation
...Invest.1994;94:1506–1512.作者：HongDu;SusanSchiavi;NickWan;MarkLevine;Dav
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InVivoActionsofAngiopoietinsonQuiescentandRemodelingBloodandLymphaticVesselsinMouseAirwaysandSkin
...onalHeart,Lung,andBloodInstitute(D.M.M.).DisclosuresNone.【参考文献】DavisS,AldrichTH,JonesPF,AchesonA,ComptonDL,JainV,RyanTE,BrunoJ,RadziejewskiC,MaisonpierrePC,YancopoulosGD.Isolationofangiopoietin-1,aligandfortheTIE2receptorbysecretion-trapexpressioncloning.Cell.1996;87:1161-1169.Maisonpier...
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AspirinandClopidogrel
...rwileJM,MoakeJL,BellWR,TarantoloSR,McCarthyLJ,SarodeR,HatfieldAJ,FeldmanMD,DavidsonCJ,TsaiHM.Thromboticthrombocytopenicpurpuraassociatedwithclopidogrel.NEnglJMed.2000;342:1773–1777.ZakarijaA,BandarenkoN,PandeyDK,AuerbachA,RaischDW,KimB,KwaanHC,McKoyJM,SchmittBP,DavidsonCJ,YarnoldPR,GorelickPB,Benn...
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QuantificationofIsoprostanesasIndicesofOxidantStressandtheRiskofAtherosclerosisinHumans
...thesestudiesisthatF2-IsoPformationissignificantlyincreasedinthisdisorder.40DavietalshowedthaturinaryF2-IsoPlevelsaresignificantlyhigherintypeIIahypercholesterolemicsubjectsby2-to3-fold.52SimilarobservationsweremadebyReillyetalinindividualswithhomozygousfamilialhypercholesterolemia.53Further,inonerep...
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Cyclooxygenase-2ExpressionandInhibitioninAtherothrombosis
...isozymebeginstoparticipate,creatinganamplificationlooptoalignarachidonicacidavailabilitywiththesustainedcapacityforprostanoidbiosynthesisbyinducibleCOX-2andPGES.Furthermore,sPLA2isresponsiblenotonlyfordelayedPGE2productionbutalsofordirectCOX-2geneinduction.87Thespecifictransmembranesignalingpathway(...
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ChangesinChromatinAccessibilityAcrosstheGM-CSFPromoteruponTCellActivationAreDependentonNuclearFactorBProteins
...mids,Dr.D.BallardforIBplasmids,andDr.G.Crabtreeforbrg1antibodies.WethankDr.DavidTremethickforcriticalreadingofthismanuscriptandmanyhelpfuldiscussions.WethankDonnaWoltringforpreparationoftheGM-CSFmutations.ThisworkwasfundedbyaProjectgrantfromtheNationalHealthandMedicalResearchCouncil,AustraliatoMFS.S...
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ChangesinChromatinAccessibilityAcrosstheGM-CSFPromoteruponTCellActivationAreDependentonNuclearFactorBProteins
...mids,Dr.D.BallardforIBplasmids,andDr.G.Crabtreeforbrg1antibodies.WethankDr.DavidTremethickforcriticalreadingofthismanuscriptandmanyhelpfuldiscussions.WethankDonnaWoltringforpreparationoftheGM-CSFmutations.ThisworkwasfundedbyaProjectgrantfromtheNationalHealthandMedicalResearchCouncil,AustraliatoMFS.S...
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Calcineurin/Nfatsignalingisrequiredforperinatallungmaturationandfunction
...logyclassificationonBiologicalProcessusingthepubliclyavailableweb-basedtoolDavid(58).TheFisherexacttestwasusedtocalculatetheprobabilityofeachgeneontologycategorythatwasoverrepresentedintheselectedlist,usingtheentireMOE430mousegenomeasareferencedataset.PearsoncorrelationidentifiedlungmRNAsthatweresim...