-
进行性骨干发育不全
【概述】称Engelmann病、骨干硬化症（diaphysealsclerosis）及camurati-Engelmann-Ribbing病等。其特征为长骨骨干对称性的梭形增大及硬化。本病罕见，有人统计男性稍多于女性，发病年龄平均为19.2岁，自3月～57岁均有。受累长骨依次为胫...
-
MolecularEvolutionaryHistoryofTubercleBacilliAssessedbyStudyofthePolymorphicNucleotidewithintheNitrateReductase(narGHJI)OperonPromoter
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.Haas,H.Heersma,G.Kllenius,E.Kassa-Kelembho,T.Koivula,H.M.Ly,A.Makristathis,C.Mammina,G.Martin,P.Mostrm,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.NgoNiobeEya...
-
CharacterizationofMycobacteriumtuberculosisComplexIsolatesfromGreekPatientswithSarcoidosisbySpoligotyping
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kelembho,H.MinhLy,A.Makristathis,C.Mammina,G.Martin,P.Mostrom,I.Morkousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.NgoNiobe-Eyangoh,J.W.Pape,V.R...
-
GeneticDiversity,DeterminedontheBasisofkatG463andgyrA95Polymorphisms,Spoligotyping,andIS6110Typing,ofMycobacteriumtuberculosisComplexIsolat
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.Haas,H.Heersma,G.Kllenius,E.Kassa-Kelembho,T.Koivula,H.M.Ly,A.Makristathis,C.Mammina,G.Martin,P.Mostrm,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.NgoNiobeEya...
-
AnalysisofMycobacteriumtuberculosisGenotypesinMadridandIdentificationofTwoNewFamiliesSpecifictoSpain-RelatedSettings
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.Haas,H.Heersma,G.Kllenius,E.Kassa-Kelembho,T.Koivula,H.M.Ly,A.Makristathis,C.Mammina,G.Martin,P.Mostrm,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.NgoNiobeEya...
-
DistributionofStrainFamiliesofMycobacteriumtuberculosisCausingPulmonaryandExtrapulmonaryDiseaseinHospitalizedChildreninCapeTown,SouthAfrica
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kelembho,H.M.Ly,A.Makristathis,C.Mammina,G.Martin,P.Mostrom,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe-Eyangoh,J.W.Pape,V.Ra...
-
OralCandidaIsolatesColonizingorInfectingHumanImmunodeficiencyVirus-InfectedandHealthyPersonsinMexico
...tionmethodwithFungitest.Diagn.Microbiol.Infect.Dis.38:11-15.Willinger,B.,E.Engelmann,H.Hofmann,S.Metzger,P.Apfalter,A.M.Hirschl,A.Makristathis,M.Rotter,B.Raddatz,andM.Seibold.2002.MulticentercomparisonofFungitestforsusceptibilitytestingofCandidaspecies.Diagn.Microbiol.Infect.Dis.44:253-257.Witthuhn,...
-
FastLigation-MediatedPCR,aFastandReliableMethodforIS6110-BasedTypingofMycobacteriumtuberculosisComplex
...Mycobacteriumtuberculosiscomplex.J.Clin.Microbiol.31:1293-1298.Haas,W.H.,G.Engelmann,B.Amthor,S.Shyamba,F.Mugala,M.Felten,M.Rabbow,M.Leichsenring,O.J.Oosthuizen,andH.J.Bremer.1999.Transmissiondynamicsoftuberculosisinahigh-incidencecountry:prospectiveanalysisbyPCRDNAfingerprinting.J.Clin.Microbiol.37...
-
ComparisonofMolecularTestsforDetectionandQuantificationofCell-AssociatedCytomegalovirusDNA
....Clin.Microbiol.38:1209-1213.vonMuller,L.,W.Hampl,J.Hinz,H.Meisel,A.Reip,E.Engelmann,R.Heilbronn,B.Gartner,O.Kramer,H.Einsele,H.Hebart,T.Ljubicic,J.Loffler,andT.Mertens.2002.Highvariabilitybetweenresultsofdifferentin-laboratorytestsforcytomegalovirus(CMV)monitoringandastandardizedquantitativeplasmaC...
-
DistributionoftheBeijingFamilyGenotypesofMycobacteriumtuberculosisinTaiwan
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kelembho,M.L.Ho,A.Makristathis,C.Mammina,G.Martin,P.Mostrom,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe-Eyangoh,J.W.Pape,V.Ra...
-
UseofRapidGenomicDeletionTypingToMonitoraTuberculosisOutbreakwithinanUrbanHomelessPopulation
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kelembho,M.L.Ho,A.Makristathis,C.Mammina,G.Martin,P.Mostrom,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe-Eyangoh,J.W.Pape,V.Ra...
-
DiscriminatoryPowerandReproducibilityofNovelDNATypingMethodsforMycobacteriumtuberculosisComplexStrains
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.H.Haas,H.Heersma,G.Kallenius,E.Kassa-Kelembho,T.Koivula,H.M.Ly,A.Makristathis,C.Mammina,G.Martin,P.Mostrom,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe...
-
MonitoringofCytomegalovirusInfectioninSolid-OrganTransplantRecipientsbyanUltrasensitivePlasmaPCRAssay
...cytes.J.Med.Virol.25:179-188.VonMuller,L.,W.Hampl,J.Hinz,H.Meisel,A.Reip,E.Engelmann,R.Heilbronn,B.Gartner,O.Kramer,H.Einsele,H.Hebart,T.Ljubicic,J.Loffler,andT.Mertens.2002.Highvariabilitybetweenresultsofdifferentin-housetestsforcytomegalovirus(CMV)monitoringandastandardizedquantitativeplasmaCMVPCR...
-
GenomicDeletionsClassifytheBeijing/WStrainsasaDistinctGeneticLineageofMycobacteriumtuberculosis
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kelembho,H.M.Ly,A.Makristathis,C.Mammina,G.Martin,P.Mostrom,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe-Eyangoh,J.W.Pape,V.Ra...
-
MolecularTypingofMycobacteriumtuberculosisbyMycobacterialInterspersedRepetitiveUnit-Variable-NumberTandemRepeatAnalysis,aMoreAccurateMethodfo
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kalembo,H.M.Li,A.Makristathis,C.Mammina,G.Martin,P.Mostrm,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe-Eyangoh,J.W.Pape,V.Rasolo...
-
NewMicrosatelliteMultiplexPCRforCandidaalbicansStrainTypingRevealsMicroevolutionaryChanges
...pes.ForensicSci.Int.118:106-113.Ruhnke,M.,A.Eigler,I.Tennagen,B.Geiseler,E.Engelmann,andM.Trautmann.1994.Emergenceoffluconazole-resistantstrainsofCandidaalbicansinpatientswithrecurrentoropharyngealcandidosisandhumanimmunodeficiencyvirusinfection.J.Clin.Microbiol.32:2092-2098.Rustchenko,E.P.1991.Vari...
-
CytotoxinandPyrogenicToxinSuperantigenGeneProfilesofStaphylococcusaureusAssociatedwithSubclinicalMastitisinDairyCowsandRelationshipswithMa
...z,K.Roschack,E.Friebe,K.Selleng,S.Lovenich,T.Greve,A.Greinacher,B.Panzig,S.Engelmann,G.Lina,andB.M.Broker.2004.egc-encodedsuperantigensfromStaphylococcusaureusareneutralizedbyhumanseramuchlessefficientlythanareclassicalstaphylococcalenterotoxinsortoxicshocksyndrometoxin.Infect.Immun.72:4061-4071.Jar...
-
EfficientDiscriminationwithinaCorynebacteriumdiphtheriaeEpidemicClonalGroupbyaNovelMacroarray-BasedMethod
...A.Cataldi,R.C.Cooksey,D.V.Cousins,J.W.Dale,O.A.Dellagostin,F.Drobniewski,G.Engelmann,S.Ferdinand,D.Gascoyne-Binzi,M.Gordon,M.C.Gutierrez,W.H.Haas,H.Heersma,E.Kassa-Kelembho,M.L.Ho,A.Makristathis,C.Mammina,G.Martin,P.Mostrm,I.Mokrousov,V.Narbonne,O.Narvskaya,A.Nastasi,S.N.Niobe-Eyangoh,J.W.Pape,V.Ras...
-
APanton-ValentineLeucocidin(PVL)-PositiveCommunity-AcquiredMethicillin-ResistantStaphylococcusaureus(MRSA)Strain,AnotherSuchStrainCarryingaMult
...z,K.Roschack,E.Friebe,K.Selleng,S.Lovenich,T.Greve,A.Greinacher,B.Panzig,S.Engelmann,G.Lina,andB.M.Broker.2004.egc-encodedsuperantigensfromStaphylococcusaureusareneutralizedbyhumanseramuchlessefficientlythanareclassicalstaphylococcalenterotoxinsortoxicshocksyndrometoxin.Infect.Immun.72:4061-4071.Ito...
-
中国现代针灸病谱研究获得初步结论
2006年09月19日中国医药报16针灸究竟能治什么病？这是世界卫生组织一直向中国针灸界提出的一个命题。经过4年的艰辛工作，由全国针灸临床研究中心副主任、天津中医药大学第一附属医院杜元灏博士领导的针灸病谱研究小组，...
-
深圳市福田区社区慢病管理影响因素分析
【摘要】目的：通过对福田区社区慢病管理影响因素的分析，提出改进措施，为社区慢病管理的发展方向提供依据。方法：对福田辖区88家社区健康服务中心进行调查，分析社区慢病管理影响因素。结果：福田区社区慢病管理存...
-
黄如方：所谓的WHO罕见病定义其实根本不存在
WHO到底有没有罕见病定义？发现一个有趣的现象，几乎所有中国媒体、患者组织、研究者，也包括很多医学专家都在引用世界卫生组织（WHO）对于罕见病的定义，大概就是“世界卫生组织（WHO）将罕见病定义为，患病人数占总人...
-
关注罕见病不能一阵风
...项活动确实达到了一定的效果，但依旧掩盖不了中国罕见病窘迫的现状。我们希望整个社会能够持续关注罕见病，更希望这一盆冷水能够把政府“浇得更清醒”。■本报记者张思玮夏秋之交，一项名为“冰桶挑战”的接力活动，...
-
尹烨带你看：罕见病的过去、现在与未来
作为中国罕见病领域最大规模的综合性论坛，9月18日“第四届中国罕见病高峰论坛”在北京如期召开。华大基因股份有限公司CEO尹烨作为嘉宾出席了论坛，并在“罕见病诊断”分论坛做了报告。报告围绕罕见病的发现史、治疗手...
-
针灸治疗中风病
...内容提要：本书系统地总结、介绍并论述了针灸治疗中风病的介入时机；选穴配伍方法；针灸工具的选择；针灸手法；针灸与其他疗法联用的方法；中风伴随病症的针灸方法等。对针灸防治中风病的机制研究作了总结和分析；系...
-
罕见病药物渐成研发主流方向受益于政府激励
...益激烈，仿制药入侵，产品研发更具挑战性，过去，罕见病药物的开发只受到较小型生物制药公司的关注，而现在逐渐吸引了大中型医药公司的兴趣。定价优势、临床需求增加，罕见病药物的市场潜力极其有利。 据最近发布...
-
“罕见病”的经济疗法
...2014年夏天的冰桶挑战让人们关注渐冻症，但这只是罕见病中的一种。因其罕见，所获得的各种资源投放也相对稀少。所以，在全球范围内加强药物研发的经济性激励、设计灵活的付费机制以及基础信息的采集则显得尤为重要。...
-
镇江市京口区2006-2007学年学生因病缺课情况分析
【摘要】目的掌握镇江市京口区中小学生因病缺课状况，以便提出防制措施。方法对2006-2007学年京口区18所中小学校23938名学生因病缺课监测资料进行统计分析。结果除节假日外，学生因病缺课全年均有发生，学生缺课最多的前4...
-
岱山县中小学生因病缺课情况分析
【关键词】疾病代价；流行病学研究；学生 学生因病缺课是反映学生健康状况的一项重要指标。为掌握岱山县中小学生因病缺课情况及发展规律，以便为学生常见病、多发病防治工作提供参考依据，笔者于1996-2006学年对岱山...
-
咳喘病外治独特新疗法——内病外治·外病外治独特新疗法丛书
...、直捷高效等特点，而深受广大群众的欢迎。本书为《内病外治·外病外治独物新疗法丛书》之分册，简要介绍了咳病外治法的起源与发展、特点与机理，详细介绍了咳喘病的外治方及其功能与主治、操作与注意事项，同时还介...